Results 181 to 190 of about 22,992,422 (339)

MOFormer: navigating the antimicrobial peptide design space with Pareto-based multi-objective transformer. [PDF]

Brief Bioinform
Wang L, Fu X, Yang J, Zhang X, Ye X, Sakurai T, Zeng X, Liu Y.   +7 more
europepmc   +1 more source

Deduction of the operable design space of RP-HPLC technique for the simultaneous estimation of metformin, pioglitazone, and glimepiride. [PDF]

Sci Rep, 2023
Marie AA, Hammad SF, Salim MM, Elkhodary MM, Kamal AH.   +4 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

From design space to green space: an analytical quality by design-assisted high-performance liquid chromatography method for the quantification of triple-combination antihypertensive drugs. [PDF]

BMC Chem
Yenduri S, Yogaraj P, Koppuravuri NP.
europepmc   +1 more source

Covering the Combinatorial Design Space of Multiplex CRISPR/Cas Experiments in Plants. [PDF]

Front Plant Sci, 2022
Van Huffel K, Stock M, Ruttink T, De Baets B.   +3 more
europepmc   +1 more source

Fuzzy sequential space-filling design [PDF]

, 2014
Dhaene, Tom, van der Herten, Joachim
core  

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Hydrogel Network Architecture Design Space: Impact on Mechanical and Viscoelastic Properties. [PDF]

Gels
Roca-Arroyo AF, Gutierrez-Rivera JA, Morton LD, Castilla-Casadiego DA.   +3 more
europepmc   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Design Space Exploration and Machine Learning Prediction of Hydrofluorocarbon Solubility in Ionic Liquids for Refrigerant Separation. [PDF]

J Chem Inf Model
Iftakher A, Hasan MMF.
europepmc   +1 more source