Results 191 to 200 of about 22,992,422 (339)

Mapping CAR T-Cell Design Space Using Agent-Based Models. [PDF]

Front Mol Biosci, 2022
Prybutok AN, Yu JS, Leonard JN, Bagheri N.   +3 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Preliminary investigation of the design space of geared magnetorheological actuators for safer robotic manipulators. [PDF]

Front Robot AI
Gingras S, St-Jean A, Plante JS.
europepmc   +1 more source

Machine learning estimation of crude oil viscosity as function of API, temperature, and oil composition: Model optimization and design space. [PDF]

PLoS One, 2023
Li D, Zhang X, Kang Q.
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Capturing the design space of meaningful human control in military systems using repertory grids. [PDF]

Front Psychol
van Diggelen J, Burken CB, Vince J.
europepmc   +1 more source

Design Space Exploration of a Multi-Model AI-Based Indoor Localization System. [PDF]

Sensors (Basel), 2022
Kotrotsios K, Fanariotis A, Leligou HC, Orphanoudakis T.   +3 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Design Space Exploration of a Sparse MobileNetV2 Using High-Level Synthesis and Sparse Matrix Techniques on FPGAs. [PDF]

Sensors (Basel), 2022
Tragoudaras A, Stoikos P, Fanaras K, Tziouvaras A, Floros G, Dimitriou G, Kolomvatsos K, Stamoulis G.   +7 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source