Results 51 to 60 of about 166,983 (266)

A Design for Inspiring Students with Near-Space Exploration

Journal of Aviation/Aerospace Education & Research, 2013
The prevalence of overseas success in engineering education represents a significant threat to the United States. Once the dominant force in advancing technology, the U.S. is seeing significant amounts of research and development work moving overseas.
Jeremy Straub, Gail Ingwalson, Ronald Fevig   +2 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Design Space Exploration of LDPC Decoders Using High-Level Synthesis

IEEE Access, 2017
Today, high-level synthesis (HLS) tools are being touted as a means to perform rapid prototyping and shortening the long development cycles needed to produce hardware designs in register transfer level (RTL).
Joao Andrade, Nithin George, Kimon Karras, David Novo, Frederico Pratas, Leonel Sousa, Paolo Ienne, Gabriel Falcao, Vitor Silva   +8 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A sparsity preserving genetic algorithm for extracting diverse functional 3D designs from deep generative neural networks

Design Science, 2020
Generative neural networks (GNNs) have successfully used human-created designs to generate novel 3D models that combine concepts from disparate known solutions, which is an important aspect of design exploration.
James D. Cunningham, Dule Shu, Timothy W. Simpson, Conrad S. Tucker   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The automated temporal burn index (ATBI) for accurate and scalable burned area mapping

International Journal of Applied Earth Observations and Geoinformation
Wildfires are recognized as essential climate variables (ECVs) due to their widespread impacts on ecosystems, greenhouse gas emissions, air quality, and the global carbon cycle. Accurate and scalable burned area mapping is therefore critical.
Muhammad Bilal
doaj   +1 more source

Prototypic Lightweight Alloy Design for Stellar‐Radiation Environments

Advanced Science, 2020
The existing literature data shows that conventional aluminium alloys may not be suitable for use in stellar‐radiation environments as their hardening phases are prone to dissolve upon exposure to energetic irradiation, resulting in alloy softening which
Matheus A. Tunes, Lukas Stemper, Graeme Greaves, Peter J. Uggowitzer, Stefan Pogatscher   +4 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source