Development of Versatile Nanoparticle System for Efficient Drug Delivery into Pulmonary Endothelium
Pediatric acute respiratory distress syndrome (PARDS) suppresses the FOXF1 transcription factor and disrupts lung development. This study shows that the FOXF1‐activating small‐molecule compound, TanFe[F], can be precisely delivered to lung endothelial cells using the innovative LEDD nanoparticle system.
Afzaal N. Mohammed +12 more
wiley +1 more source
A Multi-Level Approach to Biomimetic Design Education: Developing a Biomimetic Transfer Framework and Matrix for Design Analysis. [PDF]
Kandemir A, Kalay T.
europepmc +1 more source
Maternal Hyperglycemia Disrupts Cerebral Cortex Development Through the Foxp1‐Dll1‐Notch Axis
Maternal hyperglycemia disrupts offspring cortical development through a Foxp1–Dll1–Notch signaling axis. In a PGDM mouse model, intrauterine hyperglycemia decreases cortical thickness and perturbs neuronal layering by downregulating Foxp1, which transcriptionally regulates the Notch ligand Dll1.
Longkai He +12 more
wiley +1 more source
C-TransDance: A Style-Conditioned Gated CNN-Transformer for Real-Time Multi-Style Dance Quality Assessment Using Vision-Based Pose Sensing. [PDF]
Zhang S, Liu Y, Shin SY, Lee HA.
europepmc +1 more source
A pork belly‐inspired all‐biomass composite film was constructed through layer‐by‐layer assembly of cellulose nanofibers (CNFs), gelatin, and graphitized carbon nanosheets (GCNs) via hydrogen bonding and π–π stacking interactions. The excellent mechanical properties, effective thermal management, and outstanding EMI shielding performance of the ...
Junchao Ren +12 more
wiley +1 more source
SqueakPose Studio, an end-to-end platform for pose estimation and real-time edge-AI deployment. [PDF]
Haggerty DL, Darden CB, Lovinger D.
europepmc +1 more source
Fuyuan Huoxue decoction improves lumbar interbody fusion in rats while reducing inflammatory macrophage activity and supporting bone‐forming stem cells. Experiments implicate extracellular DNA and TLR9/NF‐κB signaling in early responses. These findings point to coordinated control of inflammation and osteogenesis as a potential route to stronger spinal
Hongwei Gao +8 more
wiley +1 more source
A retrospective comparative study of a full-course precision MDT nursing studio model integrating rational emotive behavior therapy for standardized health management during pregnancy. [PDF]
Zhang L, Tao H, Zhu L, Liu S, Yang Y.
europepmc +1 more source
Efoba, a novel bioactive component derived from aged garlic, confers neuroprotection against intracerebral hemorrhage. It acts on microglia to suppress CTSC release, inhibits NET‐mediated neural injury, and blocks pathological microglia‐neutrophil crosstalk. This study provides a highly promising lead compound for hemorrhagic‐stroke therapy.
Junjun Meng +7 more
wiley +1 more source

