Results 181 to 190 of about 94,577 (347)

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Polydrug fatal intoxication involving MDPHP: Detection and in silico investigation of multiple 3,4-methylenedioxy-derived designer drugs and their metabolites. [PDF]

J Anal Toxicol
Casati S, Ravelli A, Dei Cas M, Bergamaschi RF, Vanerio S, Sicuro L, Faraone C, Rossi M, Galante N, Mollica L, Roda G, Rota P, Battistini A.   +12 more
europepmc   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

The newest cathinone derivatives as designer drugs: an analytical and toxicological review. [PDF]

Forensic Toxicol, 2018
Majchrzak M, Celiński R, Kuś P, Kowalska T, Sajewicz M.   +4 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Sublethal Concentrations of 2C-I and 25I-NBOMe Designer Drugs Impact <i>Caenorhabditis elegans</i> Development and Reproductive Behavior. [PDF]

Int J Mol Sci
Gil-Martins E, Barbosa DJ, Cagide F, Remião F, Borges F, Silva R.   +5 more
europepmc   +1 more source

Detection and identification of designer drugs by nanoparticle-based NMR chemosensing. [PDF]

Chem Sci, 2018
Gabrielli L, Rosa-Gastaldo D, Salvia MV, Springhetti S, Rastrelli F, Mancin F.   +5 more
europepmc   +1 more source

In Vitro Toxicity Evaluation Of Piperazine Designer Drugs

, 2015
Marcelo Dutra Arbo
openalex   +2 more sources

Designer Nanoparticle-Liposome Hybrid Capsules for Drug Delivery [PDF]

, 2015
Joseph A. Zasadzinski, Jeong Eun Shin, Natalie Forbes, Maria O. Ogunyankin   +3 more
openalex   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source