Results 281 to 290 of about 94,066 (344)
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New Designer Drugs

Emergency Medicine Clinics of North America, 2021
In recent years, there has been an emergence of numerous novel drugs. Such toxicity may occur in both adolescents and adults. This article discusses the opioid epidemic and several emerging opioids, including buprenorphine, loperamide, fentanyl, fentanyl derivatives, and others.
Michael, Levine, Frank, Lovecchio
openaire   +2 more sources

Rational drug design

European Journal of Pharmacology, 2009
In this article, current knowledge of drug design is reviewed and an approach of rational drug design is presented. The process of drug development is challenging, expensive, and time consuming, although this process has been accelerated due to the development of computational tools and methodologies.
Soma, Mandal   +2 more
openaire   +2 more sources

Designer Drugs 2.0

Clinical Pharmacology & Therapeutics, 2017
This “Designer Drugs 2.0” issue of Clinical Pharmacology & Therapeutics focuses on novel psychoactive substances, primarily cannabinoids and cathinones, and the repurposing of established psychoactive compounds (e.g., modafinil, psilocybin, lysergic acid diethylamide, and 3,4‐methylenedioxymethamphetamine) that simultaneously offer new ...
M A, Huestis, R F, Tyndale
openaire   +2 more sources

Antisense Oligonucleotide Drug Design

Current Pharmaceutical Design, 2004
Maneuvering single gene expression is not only an optimal way to study gene function but also an ambitious goal, which will lead to the treatment of a variety of human diseases whose main pathogenetic event is a genetic alteration. The recent efforts focusing on the genome project have led to array based, high throughput, gene expression analysis ...
SCHIAVONE, NICOLA   +3 more
openaire   +4 more sources

Deconstructing Designer Drugs

Clinical Pharmacology & Therapeutics, 2016
The concepts behind current “designer drugs” are not new. For several centuries, chemical synthesis has made drugs more specific and more selective. However, headline designer drugs now are different and a serious public health problem because they are illicit unregulated chemical knockoffs of approved psychoactive stimulant, sedative, or perception ...
openaire   +2 more sources

DRUG DESIGN

2010
Structure-based (SBDD) and ligand-based (LBDD) drug design are extremely important and active areas of research in both the academic and commercial realms. This book provides a complete snapshot of the field of computer-aided drug design and associated experimental approaches.
openaire   +2 more sources

Antiparasitic drug design

Parasitology Today, 1989
D, Hart   +3 more
openaire   +2 more sources

Drugs by Design

Scientific American, 1993
C E, Bugg, W M, Carson, J A, Montgomery
openaire   +2 more sources

Cancer epigenetics in clinical practice

Ca-A Cancer Journal for Clinicians, 2023
Veronica Davalos, Manel Esteller
exaly  

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