Results 51 to 60 of about 8,818 (223)
Gene Expression Profiling in Familial Adenomatous Polyposis Adenomas and Desmoid Disease [PDF]
Gene expression profiling is a powerful method by which alterations in gene expression can be interrogated in a single experiment. The disease familial adenomatous polyposis (FAP) is associated with germline mutations in the APC gene, which result in ...
Nikola A Bowden +2 more
core +1 more source
Recurrent Enlarging Mesenteric Desmoid Tumor following Remote Surgical Resection
Intra-abdominal desmoid tumors are commonly associated with genetic syndromes such as familial polyposis coli. Radiological cross imaging studies such as CT and MRI are used in the preoperative work-up of such tumors.
Connie Hapgood, Allison DeLong
doaj +1 more source
In the Beginning There Was Colectomy: Current Surgical Options in Familial Adenomatous Polyposis [PDF]
Multiple colonic polyps, almost guaranteed colorectal cancer by the age of forty-five and an increased risk of non-colonic cancers characterise the autosomal dominant condition Familial Adenomatous Polyposis (FAP) 1.
McGrath Daniel R, Spigelman Allan D
core +2 more sources
The MPA mouse breast cancer model: evidence for a role of progesterone receptors in breast cancer [PDF]
More than 60% of all breast neoplasias are ductal carcinomas expressing estrogen (ER) and progesterone receptors (PR). In contrast, most of the spontaneous, chemically or MMTV induced tumors, as well as tumors arising in genetically modified mice do not ...
Bottino, Maria Cecilia +9 more
core +1 more source
Adolescents with incidental colorectal adenomas require age‐conscious management balancing referral for genetic counseling with evidence‐based surveillance. This narrative review proposes a pragmatic clinical algorithm integrating adenoma characteristics, hereditary risk assessment, and guideline‐concordant follow‐up to support individualized ...
Brett J. Hoskins +5 more
wiley +1 more source
Aggressive Fibromatosis in Neck. [PDF]
Aggressive fibromatosis (AF) is a locally aggressive infiltrative low-grade benign tumor that accounts for approximately less than 3% of all soft tissue tumors.
Bhagat, S +5 more
core
ABSTRACT Endoscopic ultrasound‐guided fine‐needle biopsy (EUS‐FNB) is widely used for the pathological diagnosis of pancreatic diseases. However, needle tract seeding (NTS) remains a clinical concern, particularly when the puncture route is not included in the surgical resection field. We report a case in which distinguishing NTS from other pathologies
Kazuya Koyama +9 more
wiley +1 more source
Oncogenic driver and therapeutic target: Prolactin signalling axis in retroperitoneal sarcoma
Retroperitoneal sarcoma cells can secrete prolactin into the bloodstream, inducing hyperprolactinaemia, which subsequently triggers metabolic reprogramming, such as glucose metabolism. SOX4 can function as a transcription factor that facilitates PRL transcription.
Fu'an Xie +21 more
wiley +1 more source
Molecular analysis of desmoid tumors with a high-density single-nucleotide polymorphism array identifies new molecular candidate lesions [PDF]
Background: Desmoid tumors are neoplastic proliferations of connective tissues. The mutation status of the gene coding for catenin (cadherin-associated protein) beta 1 (CTNNB1) and trisomy 8 on the chromosomal level have been described to have prognostic
Erben, Philipp +7 more
core +1 more source
ABSTRACT Histological biopsy is essential for diagnosing ampullary tumors; however, it can occasionally result in severe adverse events. A 49‐year‐old male underwent esophagogastroduodenoscopic screening, which revealed an ampulla of Vater with enlargement of the oral protrusion.
Tetsushi Azami +8 more
wiley +1 more source

