Results 41 to 50 of about 10,499 (199)

12-0-Tetradecanoyl phorbol-13-acetate induced differentiation in human lung squamous carcinoma cells. [PDF]

, 1992
Three human lung squamous carcinoma cell lines (NX002, CX140 and CX143) demonstrate features of squamous differentiation including involucrin synthesis and competence to form cornified envelopes.
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core   +1 more source

Autosomal dominant Carvajal plus syndrome due to the novel desmoplakin mutation c.1678A > T (p.Ile560Phe)

Molecular Genetics and Metabolism Reports, 2016
Background: Carvajal syndrome is an autosomal dominant or autosomal recessive disorder, manifesting with dilated cardiomyopathy, woolly hair, and palmoplantar keratoma. Additional manifestations can be occasionally found.
Josef Finsterer, Claudia Stöllberger, Eva Wollmann, Susanne Dertinger, Franco Laccone   +4 more
doaj   +1 more source

Paraneoplastic pemphigus: insight into the autoimmune pathogenesis, clinical features and therapy [PDF]

, 2017
Paraneoplastic pemphigus is a rare autoimmune skin disease that is always associated with a neoplasm. Usually, oral, skin, and mucosal lesions are the earliest manifestations shown by paraneoplastic pemphigus patients.
Andrea Ciofalo, Biagio Didona, Bialy-Golan, Dario Didona, Elisa Moliterni, Giannicola Iannella, Giovanni Paolino, Giuseppe Magliulo, Guido Granata, Hainsworth, Martínez De Pablo, Matz, Michele Donati, Mutasim, Nguyen, Patricia Ranuzzi, Santo Mercuri, Schepens, Stefano Calvieri, Su, Vincenzo Falasca, Zimmermann   +21 more
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Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens. [PDF]

, 2015
BackgroundTo determine differentially expressed and spliced RNA transcripts in chronic lymphocytic leukemia specimens a high throughput RNA-sequencing (HTS RNA-seq) analysis was performed.MethodsTen CLL specimens and five normal peripheral blood CD19+ B ...
A Ameur, A Choudhury, A Hidalgo, A Rosenwald, AS Kamiguti, C Haslinger, C Soo, C Trapnell, C Trapnell, CJ David, DC Gilby, E Moon, E Moravcikova, F Colotta, F Talab, FC Kelleher, Gwen Jordaan, H Dohner, H Jiang, J Eswaran, J Vilpo, JC Marioni, JJ Dongen van, JP Venables, K Inada, K Zen, L Chen, L Wang, L Yang, LQ Zhang, M Crespo, M Rehli, M Shinohara, M Sultan, Matteo Pelegrini, ML Hermiston, MW Pfaffl, N Chiorazzi, NA Twine, O Bermudez, P Guglielmi, P Kapranov, PG Ferreira, Phillipp Nham, Q Huang, RA Higgins, RI Fernando, RK Gandhirajan, RN Damle, Ryan T. Phan, S Anders, S Courtois, S Decker, S Falt, S Ibrahim, S Liu, S Ma, S Ren, S Shen, Sanjai Sharma, SM Russell, SP Shah, SR Gunn, T Ormsby, TJ Hamblin, U Klein, V Quesada, Wei Liao, XS Puente, Y Pawitan, Y Pekarsky, Y Yu, Z Wang   +72 more
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Case Report: A novel desmoplakin mutation in a taiwanese woman with familial dilated cardiomyopathy that necessitated heart transplantation

Frontiers in Genetics, 2022
Around one-third of patients diagnosed with idiopathic dilated cardiomyopathy (DCM) turn out to be familial cases, in only a few of which the identification of a pathogenic/likely pathogenic variant could be achieved. Cardiomyopathy caused by desmoplakin
Yi-Han Chang, Yi-Han Chang, Yi-Han Chang, Pei Lin, Jia-Ling Lin, Jia-Ling Lin, Hsin-Yu Huang, Chao-Kai Hsu, Chao-Kai Hsu, Chao-Kai Hsu, Chih-Hsin Hsu, Chih-Hsin Hsu   +11 more
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Striatins as plaque molecules of zonulae adhaerentes in simple epithelia, of tessellate junctions in stratified epithelia, of cardiac composite junctions and of various size classes of lateral adherens junctions in cultures of epithelia- and carcinoma-derived cells [PDF]

, 2014
Proteins of the striatin family (striatins 1–4; sizes ranging from 90 to 110 kDa on SDS-polyacrylamide gel electrophoresis) are highly homologous in their amino acid sequences but can differ in their cell-type-specific gene expression patterns and ...
Dörflinger, Yvette, Franke, Werner W., Frey, Norbert, Heid, Hans, Kuhn, Caecilia, Rickelt, Steffen, Rosin-Arbesfeld, Rina, Zimbelmann, Ralf   +7 more
core   +2 more sources

Carvajal syndrome: a brief overview and clinical case of cardiomyopathy, associated with compound heterozygous mutations of the desmoplakin gene

Российский кардиологический журнал, 2018
Mutations in the genes encoding desmosomal proteins cause a wide range of diseases associated with abnormalities of the skin, hair and heart. In 45-50% these mutations determine the development of arrhythmogenic right ventricular cardiomyopathy.
T. G. Vaikhanskaya, L. N. Sivitskaya, T. V. Kurushko, D. P. Ermakovich, E. V. Zasim, N. G. Danilenko   +5 more
doaj   +1 more source

Cell-cell adhesions and cell contractility are upregulated upon desmosome disruption. [PDF]

PLoS ONE, 2014
Desmosomes are perturbed in a number of disease states - including genetic disorders, autoimmune and bacterial diseases. Here, we report unexpected changes in other cell-cell adhesion structures upon loss of desmosome function. We found that perturbation
Kaelyn Sumigray, Kang Zhou, Terry Lechler   +2 more
doaj   +1 more source

Prostaglandin F2 Alpha Triggers the Disruption of Cell Adhesion with Cytokeratin and Vimentin in Bovine Luteal Theca Cells

Animals, 2021
Intermediate filaments (IFs) maintain cell–cell adhesions and are involved in diverse cellular processes such as cytokinesis, cell migration and the maintenance of cell structure.
Sang-Hee Lee, Seunghyung Lee
doaj   +1 more source

Syntenin-1 is a promoter and prognostic marker of head and neck squamous cell carcinoma invasion and metastasis. [PDF]

, 2016
Metastasis represents a key factor associated with poor prognosis of head and neck squamous cell carcinoma (HNSC). However, the underlying molecular mechanisms remain largely unknown. In this study, our liquid chromatography with tandem mass spectrometry
Cheng, Siliangyu, Cui, Li, Hu, Shen, Liu, Xiaojun, Messadi, Diana, Yang, Yan   +5 more
core   +1 more source