Results 81 to 90 of about 11,754 (266)

Acute Myocarditis-Like Episode in a Curly-Haired Young Boy—Red Flags for Familial Arrhythmogenic Cardiomyopathy

Diagnostics, 2020
The present case report describes a mother and son with arrhythmogenic cardiomyopathy (ACM) with early and greater left ventricle (LV) involvement. The presence of curly hair in both, together with the resuscitated sudden cardiac death of the mother ...
Alina Elena Pătru, Sebastian Onciul, Adrian Sturzu, Eliza Cinteză, Eleonora Gima, Bogdan A. Popescu, Philippe Chevalier, Ruxandra Jurcuț   +7 more
doaj   +1 more source

Prostaglandin F2 Alpha Triggers the Disruption of Cell Adhesion with Cytokeratin and Vimentin in Bovine Luteal Theca Cells

Animals, 2021
Intermediate filaments (IFs) maintain cell–cell adhesions and are involved in diverse cellular processes such as cytokinesis, cell migration and the maintenance of cell structure.
Sang-Hee Lee, Seunghyung Lee
doaj   +1 more source

Desmoplakin is required for microvascular tube formation in culture [PDF]

Journal of Cell Science, 2004
Desmoplakin (DP) is a key component of cellular adhesion junctions known as desmosomes; however, recent investigations have revealed a novel location for DP in junctions separate from desmosomes termed complexus adherens junctions. These junctions are found at contact sites between endothelial cells that line capillaries.
Bonnie Hoel, G. Ian Gallicano, Xuan Zhou, August Stuart, Luis Dettin, Gisela Rodriguez   +5 more
openaire   +3 more sources

Striatins as plaque molecules of zonulae adhaerentes in simple epithelia, of tessellate junctions in stratified epithelia, of cardiac composite junctions and of various size classes of lateral adherens junctions in cultures of epithelia- and carcinoma-derived cells [PDF]

, 2014
Proteins of the striatin family (striatins 1–4; sizes ranging from 90 to 110 kDa on SDS-polyacrylamide gel electrophoresis) are highly homologous in their amino acid sequences but can differ in their cell-type-specific gene expression patterns and ...
Dörflinger, Yvette, Franke, Werner W., Frey, Norbert, Heid, Hans, Kuhn, Caecilia, Rickelt, Steffen, Rosin-Arbesfeld, Rina, Zimbelmann, Ralf   +7 more
core   +2 more sources

Premature Termination Codon in 5′ Region of Desmoplakin and Plakoglobin Genes May Escape Nonsense-Mediated Decay through the Reinitiation of Translation

International Journal of Molecular Sciences, 2022
Arrhythmogenic cardiomyopathy is a heritable heart disease associated with desmosomal mutations, especially premature termination codon (PTC) variants. It is known that PTC triggers the nonsense-mediated decay (NMD) mechanism.
M. Vallverdú-Prats, R. Brugada, M. Alcalde   +2 more
semanticscholar   +1 more source

Identification of the initial molecular changes in response to circulating angiogenic cells-mediated therapy in critical limb ischemia [PDF]

, 2020
BackgroundCritical limb ischemia (CLI) constitutes the most aggressive form of peripheral arterial occlusive disease, characterized by the blockade of arteries supplying blood to the lower extremities, significantly diminishing oxygen and nutrient supply.
A Carrizzo, A Limbourg, A Schroll, A Taguchi, A Zampetaki, AI Khan, AL Hemdahl, C Hu, C Kalka, C Seignez, C Xia, CH Yoon, D Sukmawati, DH Walter, DM Dunlea, DN Prater, E Chavakis, EB Jude, EC Watson, EE Vaughan, EL Simpson, F Du, F Sabatier, F Vinchi, FG Fowkes, FM Vega, G Cao, G Dragneva, GO Ouma, H Chen, HH Chopra, J Patel, J Rehman, J Zhang, JA Smith, JA Vizcaino, JG Tidball, JK Meisner, JL Anderson, JL Dong, JP Cooke, JX Yang, JY Kim, K Banno, K Funakoshi, L Bao, L Norgren, L Wu, LJ Druhan, M Hassanpour, M Qadura, M Rahmani, M Rigato, MS Conte, N Edwards, P Sangwung, Q Dai, Q Xie, R Donato, R Lara-Hernandez, R Tanaka, RC Savani, RH Lee, RJ Medina, RW Sprengers, S Hazarika, S Janciauskiene, S Nolan, SH Ko, SL Hsu, SM Krishna, SW Kim, T Asahara, UJ Sachs, V Abella, V Weel van, W Song, WC Shen, X Wang, X Zhou, Y Fujita, Y Ye, Z Yang   +82 more
core   +1 more source

Recurrent immunosuppressive-responsive myocarditis in a patient with desmoplakin cardiomyopathy: a case report

European Heart Journal: Case Reports
Background Desmoplakin (DSP) cardiomyopathy is a rare genetic condition characterized by repeated inflammatory myocardial injury and is associated with ventricular arrhythmia and sudden cardiac death.
H. McColl, Rachael Cordina, Sean Lal, M. Parker, Imre Hunyor, C. Medi, Belinda Gray   +6 more
semanticscholar   +1 more source

Long noncoding RNA LYPLAL1-AS1 regulates adipogenic differentiation of human mesenchymal stem cells by targeting desmoplakin and inhibiting the Wnt/β-catenin pathway

Cell Death Discovery, 2021
Long noncoding RNAs are crucial factors for modulating adipogenic differentiation, but only a few have been identified in humans. In the current study, we identified a previously unknown human long noncoding RNA, LYPLAL1-antisense RNA1 (LYPLAL1-AS1 ...
Yanlei Yang, Junfen Fan, Haoying Xu, L. Fan, Luchan Deng, Jing Li, Di Li, Hongling Li, Fengchun Zhang, R. Zhao   +9 more
semanticscholar   +1 more source

Arrhythmogenic right ventricular cardiomyopathy associated with severe left ventricular involvement in a cat. [PDF]

, 2009
An 8-year-old, 4 kg, intact female, domestic shorthaired cat was referred for tachypnea and pleural effusion. A 24-h Holter recording showed numerous polymorphic ventricular premature complexes with left and right bundle branch block morphology ...
Basso C, CIARAMELLA, PAOLO, Di Loria A, PIANTEDOSI, DIEGO   +3 more
core   +1 more source

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source