Background: The majority of the patients affected by a new variant of endemic pemphigus foliaceus in El Bagre, Colombia (El Bagre EPF or pemphigus Abreu-Manu), have experienced vision problems; we have previously reported several ocular abnormalities.
Ana Maria Abreu-Velez +2 more
doaj +2 more sources
We developed immunohistochemical and image analytical techniques to localize and quantify keratins and desmoplakins in sections of plastic-embedded human gingiva.
R. Carmichael, C. McCulloch, G. A. Zarb
semanticscholar +2 more sources
FDG PET/CT imaging and circulating biomarkers of inflammation in desmoplakin cardiomyopathy. [PDF]
Abstract Aims Inflammation has been implicated in the pathogenesis of desmoplakin (DSP) cardiomyopathy, and retrospective studies have described abnormal myocardial fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) findings in symptomatic patients eventually diagnosed with DSP cardiomyopathy.
Divakaran S +10 more
europepmc +2 more sources
Morphological Characterization of Intrafollicular Epithelial Bodies (IFEBs) in Rabbit Peyer's Patches. [PDF]
Follicle-associated epithelium (FAE) covering the lymphoid follicles of Peyer’s patches (PPs) plays a central role in mucosal immunity. Here, we investigated FAE-derived intrafollicular epithelial bodies (IFEBs) that apparently detach from the FAE and ...
Tamborrino T +9 more
europepmc +4 more sources
Persistence of both peripheral and non-peripheral corneodesmosomes in the upper stratum corneum of winter xerosis skin versus only peripheral in normal skin. [PDF]
To understand the biochemical abnormalities that underlie the reduced desquamation observed in dry skin, we analyzed corneodesmosome degradation in normal and winter xerosis skin.
M. Simon +7 more
semanticscholar +2 more sources
Subclinical oral involvement in patients with endemic pemphigus foliaceus
Background: We have described a variant of endemic pemphigus foliaceus (EPF) in El Bagre area known as pemphigus Abreu-Manu. Our previous study suggested that Colombian EPF seemed to react with various plakin family proteins, such as desmoplakins ...
Ana Maria Abreu-Velez +3 more
doaj +1 more source
Periplakin, a novel component of cornified envelopes and desmosomes that belongs to the plakin family and forms complexes with envoplakin [PDF]
The cornified envelope is a layer of transglutaminase cross-linked protein that is assembled under the plasma membrane of keratinocytes in the outermost layers of the epidermis.
Christiana Ruhrberg +7 more
core +1 more source
Overlapping Distribution of Autoantibody Specificities in Paraneoplastic Pemphigus and Pemphigus Vulgaris [PDF]
Paraneoplastic pemphigus is an autoimmune bullous skin disease in which autoantibodies immunoprecipitate a characteristic antigenic complex. The objective of this study was to analyze by immunoblotting and immunoelectron microscopy the autoimmune ...
Catherine Prost +17 more
core +1 more source
Expression of Albatross and desmoplakins in the thymi of keratin 8-deficient mice.
Immunofluorescence staining of thymus sections of 7-week-old wild-type FVB/N mice (WT) and K8-deficient FVB/N mice (K8 KO) was performed to detect CD205 (A) or desmoplakins I/II (C) (green) and Albatross (A) (red). (A) Whereas colocalization of CD205 and
Chikako Odaka (462390) +8 more
core +1 more source
Envoplakin, a novel precursor of the cornified envelope that has homology to desmoplakin [PDF]
The cornified envelope is a layer of transglutaminase cross-linked protein that is deposited under the plasma membrane of keratinocytes in the outermost layers of the epidermis.
Dooley, TP +9 more
core +1 more source

