Results 101 to 110 of about 36,917 (245)
Rare Secondary Neoplasms Arising in Epidermal Nevus: A Case Series and Literature Review
Journal of Cutaneous Pathology, EarlyView.ABSTRACT Malignant transformation is known to occur with many nevi, such as nevus sebaceus. However, cases of secondary tumors developing in an epidermal nevus (EN) are rare, with only a few case reports documented in the literature. We present three unique cases of syringocystadenoma papilliferum (SCAP), syringofibroadenoma, trichilemmoma, and basal ...
Haya A. Homsi +5 more
wiley +1 more source
Superficial Ewing Sarcoma of the Rectum: A Case Report and the Utility of Molecular Diagnostics
Journal of Cutaneous Pathology, EarlyView.ABSTRACT Ewing sarcoma is an undifferentiated small round cell sarcoma that most commonly presents as a malignant bone tumor in pediatric and young adult patients. The diagnosis is typically confirmed by molecular genetic identification of a fusion protein, most commonly involving members of the FET and ETS gene families.
Jessica L. Muldoon +3 more
wiley +1 more source
Unique metabolic features of pancreatic cancer stroma: relevance to the tumor compartment, prognosis, and invasive potential. [PDF]
, 2015 Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis. The aggressiveness and therapeutic recalcitrance of this malignancy has been attributed to multiple factors including the influence of an active desmoplastic stroma.
Balaji, Uthra +4 more
core +2 more sources
The FEBS Journal, EarlyView.Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley +1 more source
A Case of Multiple Desmoplastic Trichoepithelioma [PDF]
, 2016 Letter to the ...
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core +2 more sources
A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer
The FEBS Journal, EarlyView.Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou +4 more
wiley +1 more source
The FEBS Journal, EarlyView.The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka +3 more
wiley +1 more source
Peripheral Ameloblastoma with Mixed Histological Patterns
Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2015 Peripheral ameloblastoma is a relatively uncommon neoplasm of odontogenic origin histologically resembles the classic ameloblastoma and derived from epithelial and/or mesenchymal elements being part of the tooth forming apparatus. It can be originated in
Manas Bajpai, Nilesh Pardhe
doaj
A rare case of palmar congenital nevus with sclerodermoid reaction
Clinical Case ReportsKey Clinical Message Palmar congenital nevus with sclerodermoid reaction has not been reported. It has the potential of deep extension following the fibrous bundle.
Chengbei Bao +3 more
doaj +1 more source
World Health Organization classification of tumours of the breast 6th edition 2026
Histopathology, EarlyView.The 6th edition of the World Health Organization Classification of Breast Tumours introduces changes based on recent advances in our understanding of breast biology, developments in diagnostic modalities, identification of specific molecular targets and new treatment regimes.
Cecily Quinn +47 more
wiley +1 more source