Results 21 to 30 of about 17,288 (263)

Development and Validation of a Liquid Chromatography High-Resolution Mass Spectrometry Method for Blood Desmopressin Quantification and Its Application in Hemophilia A Patients. [PDF]

Rapid Commun Mass Spectrom
ABSTRACT Desmopressin (DDAVP), which indirectly increases Coagulation Factor VIII concentrations in the blood, is a common treatment for bleeding disorders such as von Willebrand disease or hemophilia A. However, DDAVP exhibits significant variability in response due to interindividual differences in pharmacokinetics.
Hodin S, Escal J, Feliu C, Pontis A, Josset L, Serban A, Guillet B, Delavenne X.   +7 more
europepmc   +2 more sources

Desmopressin as a hemostatic and blood sparing agent in bleeding disorders

European Journal of Haematology, 2023
Intranasal, subcutaneous, or intravenous desmopressin can be utilized to release von Willebrand Factor and Factor VIII into circulation, enhance platelet adhesion and shorten bleeding time.
Ajay Mohinani, Sarah Patel, Virginia Tan, Thomas Kartika, S. Olson, T. Deloughery, J. Shatzel   +6 more
semanticscholar   +1 more source

Role of Desmopressin Acetate before Percutaneous Ultrasound-Guided Kidney Biopsy in Patients with Kidney Dysfunction

Indian Journal of Nephrology, 2023
Background: The most common complication of percutaneous kidney biopsy is bleeding, which can be seen in up to one-third of cases. The aim of this study was to evaluate the effect of prebiopsy administration of intranasal desmopressin acetate in reducing
J. Sethi, Sandeep Bansal, Anupam Lal, H. Kohli, Manish Rathi   +4 more
semanticscholar   +1 more source

Acquired von Willebrand Syndrome and Desmopressin Resistance During Venovenous Extracorporeal Membrane Oxygenation in Patients With COVID-19: A Prospective Observational Study

Critical Care Medicine, 2022
OBJECTIVES: Although COVID-19 is associated with high von Willebrand factor (vWF) parameters promoting thrombosis, venovenous extracorporeal membrane oxygenation (vvECMO) is associated with the development of acquired von Willebrand syndrome (AVWS ...
J. Kalbhenn, H. Glonnegger, M. Büchsel, H. Priebe, B. Zieger   +4 more
semanticscholar   +1 more source

Predicting the Need for Desmopressin Treatment During Inpatient and After Discharge Following Endoscopic Sellar Surgery

Frontiers in Neurology, 2022
IntroductionPostoperative diabetes insipidus (DI) is a common complication following endoscopic sellar surgery. However, the requirement of desmopressin treatment for patients with DI are heterogenous.
Chia-En Wong, Wei-Hsin Wang, Wei-Hsin Wang, Ming-Ying Lan, Ming-Ying Lan, Po-Hsuan Lee, Chi-Chen Huang, Pei-Fang Su, Jung-Shun Lee, Jung-Shun Lee, Jung-Shun Lee   +10 more
doaj   +1 more source

Mucoadhesive Electrospun Nanofiber-Based Hybrid System with Controlled and Unidirectional Release of Desmopressin

International Journal of Molecular Sciences, 2022
The sublingual mucosa is an attractive route for drug delivery, although challenged by a continuous flow of saliva that leads to a loss of drug by swallowing.
Mai Bay Stie, J. Gätke, I. Chronakis, J. Jacobsen, H. M. Nielsen   +4 more
semanticscholar   +1 more source

Desmopressin response depends on the presence and type of genetic variants in patients with type 1 and type 2 von Willebrand disease

Blood Advances, 2022
Key Points All type 1 VWD patients without a VWF gene variant have a complete response to desmopressin. In type 1 and type 2 VWD patients with a VWF gene variant, desmopressin response highly depends on the causative VWF gene variant.
F. Atiq, J. Heijdra, Fleur Snijders, J. Boender, E. Kempers, W. V. van Heerde, D. Maas, Sandy Krouwel, S. Schoormans, J. de Meris, S. Schols, K. V. van Galen, J. G. van der Bom, M. Cnossen, K. Meijer, K. Fijnvandraat, J. Eikenboom, F. Leebeek   +17 more
semanticscholar   +1 more source

Korean guideline of desmopressin for the treatment of nocturia in men [PDF]

Investigative and Clinical Urology, 2022
Purpose: Nocturia is the most bothersome of lower urinary tract symptoms in men. Desmopressin, a synthetic analog of the human hormone vasopressin, has been used for the treatment of nocturia.
Eu Chang Hwang , Hyun Jin Jung, Mi Ah Han, Myung Ha Kim, Seong Hyeon Yu, Hyun Cheol Jeong, Jun Seok Kim, Sung Hyun Paick, Jeong Kyun Yeo , Jae Hung Jung   +9 more
doaj   +1 more source

Cocaine use disorder patients develop distinct patterns of regulation of acth secretion by a vasopressin agonist and oxytocin: Report on a laboratory study

Drug and Alcohol Dependence Reports, 2023
Background: : Oxytocin and Vasopressin systems in the brain sustain adaptation to stressors. Cocaine being a stressor, it may alter brain homeostatic function. This dysregulation may entrench cocaine use disorder.
Wilfrid Noël Raby, Matthew Heller, Demetrios Milliaressis, C. Jean Choi, Cale Basaraba, Frances R. Levin, Sarah Church, Martina Pavlicova, Edward V. Nunes   +8 more
doaj   +1 more source

IS DESMOPRESSIN USEFUL IN THE EVALUATION OF CUSHING'S SYNDROME?

Journal of Clinical Endocrinology and Metabolism, 2022
The desmopressin test was first described 30 years ago. Based on the differential secretagogue properties of desmopressin on ACTH release between normal and corticotroph tumor cells, this test was intended to facilitate the diagnosis of Cushing's ...
F. Castinetti, A. Lacroix
semanticscholar   +1 more source