Results 41 to 50 of about 9,080 (167)

Preimplantation Genetic Testing for Families at Risk of Haemophilia: Ten‐Year Single‐Centre Experience

Haemophilia, EarlyView.
ABSTRACT Introduction Preimplantation genetic testing for monogenic diseases (PGT‐M) is a reproductive option for couples at high risk of transmitting inherited disorders. We report a ten‐year single‐centre PGT‐M experience in families at risk of hemophilia.
Mimosa Mortarino, Isabella Garagiola, Valeria Nicotra, Alessandra Riccaboni, Cristina Guarneri, Edgardo Somigliana, Flora Peyvandi   +6 more
wiley   +1 more source

Evaluation of the management outcomes of primary mono-symptomatic nocturnal enuresis among sudanese children: A retrospective study

Journal of Medical Sciences, 2021
Background: Nocturnal enuresis or bedwetting is the most common type of urinary incontinence in children. The wide prevalence of nocturnal enuresis speaks to the need for an improved understanding of this condition by others to improve the management ...
Nafhat Elhag Yousif, Safaa Badi, Bashir Alsiddig Yousef   +2 more
doaj   +1 more source

Symptoms, Diagnosis, and Treatment for Women and Girls With Hemophilia: A Narrative Review

Haemophilia, EarlyView.
ABSTRACT Introduction Hemophilia is an X‐linked bleeding disorder previously thought to present only in men. This sentiment is rapidly changing as the information around women and girls’ experiences of bleeding symptoms has evolved, sparking intense discussion among researchers, clinicians, patients, and patient advocates regarding appropriate ...
Sam Hirniak, Carla Samuel, Faria Aditi, Haya Abu Ghazaleh, Dawn Rotellini, Menaka Pai, Andrea Edginton   +6 more
wiley   +1 more source

Desmopressin and the risk of hyponatremia: A population-based cohort study.

PLoS Medicine, 2019
BACKGROUND:Desmopressin was approved by the Food and Drug Administration (FDA) in 1978 for use in diabetes insipidus and bleeding disorders, but it is also prescribed off-label for patients with nocturia.
Michael Fralick, Sebastian Schneeweiss, Christopher J D Wallis, Emily H Jung, Aaron S Kesselheim   +4 more
doaj   +1 more source

How I Investigate Bleeding Disorders of Unknown Cause: Current Diagnostic Pathways and Gaps in Laboratory Investigation

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Bleeding disorder of unknown cause (BDUC) constitutes the largest group of patients presenting with a mild‐to‐moderate bleeding tendency in tertiary care settings. Their clinical bleeding phenotype is characterized by mucocutaneous bleeding, as well as bleeding following surgical challenges or childbirth, and is associated with impaired health‐
Dino Mehic, Faris Karaselimovic, Tim Dreier, Johanna Gebhart   +3 more
wiley   +1 more source

Clinical and Laboratory Characterization of Acquired Von Willebrand Syndrome

American Journal of Hematology, Volume 101, Issue 9, Page 2147-2156, September 2026.
ABSTRACT Acquired von Willebrand Syndrome (AVWS) is a rare bleeding disorder characterized by quantitative or qualitative defects of von Willebrand factor (VWF) in patients without a personal or family history of bleeding. It is frequently associated with systemic diseases, particularly lymphoproliferative disorders (LPDs) and myeloproliferative ...
Alessandro Ciavarella, Luciano Baronciani, Omid Seidizadeh, Paola Colpani, Elio Ingenito, Daniele Cattaneo, Maria Teresa Pagliari, Addolorata Truma, Alessandra Iurlo, Simona Maria Siboni, Flora Peyvandi   +10 more
wiley   +1 more source

A comparative study of intranasal desmopressin and intranasal ketamine for pain management in renal colic patients: a randomized double-blind clinical trial [PDF]

Clinical and Experimental Emergency Medicine
Objective Urolithiasis is one of the most common urological diseases worldwide, usually presenting as renal colic that leads to severe pain that requires analgesic treatment.
Farhad Heydari, Reza Azizkhani, Saeed Majidinejad, Majid Zamani, Aref Norouzian   +4 more
doaj   +1 more source

Age and Nocturnal Polyuria in Nocturia: A Multicenter Voiding Diary Cohort Study

Neurourology and Urodynamics, Volume 45, Issue 7, Page 1398-1404, September 2026.
ABSTRACT Introduction Although the prevalence of nocturnal polyuria (NP) increases with age, the mechanisms underlying age‐related changes in voiding patterns and the daytime–nighttime distribution of urine volume remain unclear. Given that the severity of nocturia and bladder function may differ across age groups, age‐specific voiding profiles require
Kota Kawase, Yoshinori Nishino, Kanako Matsuoka, Shunta Makabe, Ryo Tanji, Hiroki Hoshino, Kei Kawada, Kousei Miwa, Masayuki Tomioka, Tomoki Taniguchi, Koji Iinuma, Yuki Tobisawa, Keita Nakane, Yoshiyuki Kojima, Takahiko Mitsui, Takuya Koie   +15 more
wiley   +1 more source

Platelet function in patients undergoing major non‐cardiac vascular surgery (PLUGS): a prospective cohort study*

Anaesthesia, Volume 81, Issue 9, Page 1236-1244, September 2026.
Summary Introduction Patients who require major vascular surgery often receive antiplatelet therapy for primary or secondary prevention of cardiovascular disease. Clopidogrel resistance and variability in platelet recovery after drug discontinuation pose clinical challenges, particularly for regional anaesthesia and blood management.
Akshay Shah, Grace Polley, Kasia Bera, Keith Maher, Stephen Von‐Kier, Antonio Barbosa, Louis Corrigan, Sabeena Sharma, Peter Baker, Stuart R. McKechnie, Michael J. Desborough, on behalf of the PLUGS Investigators   +11 more
wiley   +1 more source

The Rate of Relapse of Primary Monosymptomatic Nocturnal Enuresis with Desmopressin Treatment in Comparison with Combined Treatment of Desmopressin and Tolterodine in Children Aged 5 to 16 Years [PDF]

Iranian South Medical Journal
Background: In the process of treating children with primary monosymptomatic nocturnal enuresis (PMNE), the relapse of PMNE after stopping the medicine causes the child to take the medicine for a prolonged time.
Fereshteh Sobhani, Banafsheh Arad, Abolfazl Mahyar, Ameneh Barikani   +3 more
doaj