Results 51 to 60 of about 9,080 (167)

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

open access: yesActa Ophthalmologica, Volume 104, Issue 6, Page e630-e647, September 2026.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen   +3 more
wiley   +1 more source

Protective effects of Desmopressin acetate on retention of spatial memory deficits induced by post-traumatic stress disorder in Rats

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2012
Background and Objective: Post-traumatic stress disorder (PTSD) impairs spatial learning and memory. Desmopressin acetate ameliorates the cognitive deficits induced by electroconvulsive shock. This study was designed to evaluate the protective effects of
Mehrabadi S   +3 more
doaj  

Long‐term outcomes in patients with postural orthostatic tachycardia syndrome with an average follow‐up of over 20 years

open access: yesJournal of Internal Medicine, Volume 300, Issue 3, Page 299-311, September 2026.
Abstract Background Postural orthostatic tachycardia syndrome (POTS) is a chronic form of orthostatic intolerance that primarily affects female patients. There are scarce data evaluating the long‐term outcomes in POTS. Objectives This study sought to evaluate the long‐term impacts of POTS over multiple decades in adult patients.
Kate M. Bourne   +11 more
wiley   +1 more source

Open‐Label, Balanced, Randomized, Single‐Dose, Three‐Treatment, Three‐Sequence, Three‐Period, Three‐Way Crossover Oral Bioequivalence Study of Desmopressin Acetate Oral Solution

open access: yesClinical Pharmacology in Drug Development, Volume 15, Issue 8, August 2026.
ABSTRACT Desmopressin is first‐line therapy for central diabetes insipidus, also known as arginine vasopressin deficiency, but presents dosing challenges due to its narrow therapeutic index. This open‐label, randomized, three‐way crossover study evaluated the bioequivalence of a new desmopressin acetate oral solution (50 mcg/mL) compared to ...
Adam Christensen   +5 more
wiley   +1 more source

Variables Affecting Periprocedural Haemostatic Response in Patients With Haemophilia: Real‐World Retrospective Study

open access: yeseJHaem, Volume 7, Issue 4, August 2026.
ABSTRACT Introduction Patients with haemophilia (PWH) undergoing invasive procedures are at increased risk of periprocedural bleeding, and optimal haemostatic response (HR) depends on patient‐ and procedure‐related factors. We aimed to evaluate variables associated with HR in PWH undergoing invasive procedures.
Jose Antonio Sanchez Salas   +3 more
wiley   +1 more source

Pufferfish exposure and presumed tetrodotoxicosis in Australian dogs: 372 cases (2007–2018)

open access: yesAustralian Veterinary Journal, Volume 104, Issue 8, Page 497-508, August 2026.
Introduction Tetrodotoxin (TTX) is a neurotoxin found in pufferfish that results in the blockade of excitatory conduction and clinical signs including gastrointestinal upset and paralysis. The objectives of this study were to describe the epidemiology of pufferfish exposure and presumed tetrodotoxicosis in dogs, and to determine associations with the ...
J Hanson, CR Sharp, EM Leister
wiley   +1 more source

Transdermal Delivery of Desmopressin Acetate from Water-in- Oil Nano/submicron Emulsion Systems [PDF]

open access: yesIranian Journal of Chemical Engineering, 2016
Desmopressin acetate is a potent synthetic peptide hormone. A more acceptable route of Desmopressin acetate is a potent synthetic peptide hormone. That is administered via parenteral, intranasal, and oral routes. A more acceptable route of administration
Arezou Soroushnia   +2 more
doaj  

Selection of AVP-Shortage Patients as Candidates for Low-Dose Oral Desmopressin Administration

open access: yesResearch and Reports in Urology, 2021
Takumi Takeuchi,1 Kazuki Maki,1 Yumiko Okuno,1 Mami Hattori-Kato,2 Koji Mikami1 1Department of Urology, Japan Organization of Occupational Health and Safety, Kanto Rosai Hospital, Nakahara-ku, Kawasaki, Japan; 2Department of Urology, Tokyo Teishin ...
Takeuchi T   +4 more
doaj  

Towards a Safe and Effective Lithium Therapeutic Range for Older Adults With Bipolar Disorder: An ISBD Task Force Systematic Review

open access: yesBipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Objectives Lithium is recommended as the first‐line maintenance treatment for older adults with bipolar disorder (OABD). However, age‐related reduction in renal clearance, heightened sensitivity to adverse effects, and drug interactions increase the risk of toxicity and necessitate lower therapeutic serum levels in this population.
Paula V. Nunes   +15 more
wiley   +1 more source

Genetic Insights Into AVP Deficiency: Identification of a Novel AVP Variant and Compilation of a Curated Catalogue of Pathogenic Variants

open access: yesClinical Genetics, Volume 110, Issue 2, Page 203-209, August 2026.
We identified a novel pathogenic AVP variant in two Danish families with autosomal dominant inheritance of symptoms of AVP deficiency. In addition, we compiled a catalogue of additionally 109 AVP variants that cause AVP deficiency and demonstrated the advantage of combining expert‐assisted curation, literature search, and online repositories to ensure ...
Jennifa Joseph   +5 more
wiley   +1 more source

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