[1-Deamino-4-Cyclohexylalanine] Arginine Vasopressin: A Potent and Specific Agonist for Vasopressin V1b Receptors [PDF]
To date, there are no vasopressin (VP) agonists that exhibit a high affinity and selectivity for the VP V1b receptor with respect to the V1a, V2, and oxytocin receptors. In this study, we describe the synthesis and pharmacological properties of [1-deamino-4-cyclohexylalanine] arginine vasopressin (d[Cha4]AVP).
L L Cheng, S Stoev, Mauro Giacomini
exaly +5 more sources
1. Anterolateral cut (ALC) of the medial basal hypothalamus (MBH) in rats produces an elevation of plasma catecholamine levels, especially of norepinephrine (NE), in unstressed animals and a more pronounced rise of plasma NE levels in response to immobilization (IMO).
R Kvetnansky +2 more
exaly +5 more sources
In order to elucidate the mechanism(s) responsible for the prolonged antidiuretic activity of 1-deamino-[8-D-arginine]-vasopressin (dDAVP), antidiuretic activities of dDAVP and arginine vasopressin (AVP) were determined in the rat following either oral administration or incubation with AVP-degrading enzymes and reagents. Oral administration of dDAVP to
Kuniaki Matsui +6 more
openalex +4 more sources
The effects of infusions of arginine vasopressin or 1‐deamino‐8‐D‐arginine vasopressin on common carotid vascular resistance in conscious, Long Evans rats [PDF]
Intravenous infusions of arginine vasopressin or 1‐deamino‐8‐d‐arginine vasopressin (DDAVP) were given to conscious, Long Evans rats chronically instrumented with bilateral, common carotid, pulsed Doppler probes and intravascular catheters. During infusion of vasopressin at 0.3 nmol min−1 there was an increase in common carotid vascular resistance ...
Sheila M. Gardiner +2 more
openalex +4 more sources
Cyclic-AMP regulates postnatal development of neural and behavioral responses to NaCl in rats. [PDF]
During postnatal development rats demonstrate an age-dependent increase in NaCl chorda tympani (CT) responses and the number of functional apical amiloride-sensitive epithelial Na+ channels (ENaCs) in salt sensing fungiform (FF) taste receptor cells ...
Jie Qian +12 more
doaj +5 more sources
DDAVP (desmopressin; 1‐deamino‐cys‐8‐
We tested the response to desmopressin (1‐deamino‐cys‐8‐d‐arginine‐vasopressin; DDAVP) in four patients with haemophilia B [factor IX (F IX) at diagnosis 1·4–5%]. The activated partial thromboplastin time (aPTT) was significantly shortened in all patients.
Stephan Ehl, Thomas Severin, A. H. Sutor
openalex +4 more sources
Desmopressin use in major cardiac surgery is associated with renal impairment: a retrospective single-center analysis [PDF]
Background Desmopressin acetate (1-deamino-8-d-arginine vasopressin—DDAVP) is a analogue of the antidiuretic hormone vasopressin. DDAVP is suggested to reduce bleeding after cardiac surgery using cardiopulmonary bypass.
Andreas Koköfer +5 more
doaj +2 more sources
How should abnormal uterine bleeding be managed in people with bleeding disorders: a systematic review of the literature and thematic synthesis [PDF]
Abnormal uterine bleeding (AUB) describes any bleeding from the uterus that deviates from the norm in terms of regularity, duration, or volume. AUB is a common condition that can significantly affect quality of life. Although inherited bleeding disorders
Rameen Masood +8 more
doaj +2 more sources
Efficacy of adjusted weight-based dosing of desmopressin (1-deamino-8-d-arginine vasopressin in type 1 von Willebrand disease. [PDF]
Seaman CD.
europepmc +2 more sources
Korean guideline of desmopressin for the treatment of nocturia in men [PDF]
Purpose: Nocturia is the most bothersome of lower urinary tract symptoms in men. Desmopressin, a synthetic analog of the human hormone vasopressin, has been used for the treatment of nocturia.
Eu Chang Hwang +9 more
doaj +1 more source

