PFA-100 test in the detection of platelet dysfunction and monitoring DDAVP in a patient with liver cirrhosis undergoing inguinal hernia repair [PDF]
Introduction. Hemostatic abnormalities in liver cirrhosis are complex and multifactorial and may predispose to prolonged hemorrhage following invasive procedures.
Vučelić Dragica +2 more
doaj +1 more source
Cyclic-AMP regulates postnatal development of neural and behavioral responses to NaCl in rats. [PDF]
During postnatal development rats demonstrate an age-dependent increase in NaCl chorda tympani (CT) responses and the number of functional apical amiloride-sensitive epithelial Na+ channels (ENaCs) in salt sensing fungiform (FF) taste receptor cells ...
Jie Qian +12 more
doaj +1 more source
Central Adrenal Insufficiency and Diabetes Insipidus Misdiagnosed as Severe Depression
A 68 year-old Japanese man, who had been suffering from immobilization and disuse syndrome, was admitted to our hospital for evaluation of polyuria with polyposia, hyponatremia and low blood pressure.
Naoki Hiroi +4 more
doaj +1 more source
Use of Desmopressin in Hyponatremia: Foe and Friend
Use of desmopressin (1-deamino-8-d-arginine vasopressin; DDAVP), a synthetic vasopressin receptor agonist, has expanded in recent years. Desmopressin leads to renal water retention, and iatrogenic hyponatremia may result if fluid intake is not ...
Steven G. Achinger, Juan Carlos Ayus
doaj +1 more source
Background Acquired von Willebrand syndrome (AVWS) has been associated with monoclonal gammopathy of undetermined significance (MGUS), with limited data on its management. Methods We conducted a systematic literature search in Medline (Ovid), Embase, and
Mouhamed Yazan Abou‐Ismail +3 more
doaj +1 more source
Platelet Levels Associated With Bleeding Risk for Dental Interventions: A Systematic Review
ABSTRACT Objectives To evaluate evidence in relation to postoperative bleeding in humans aged ≥ 16 with preoperative platelet counts < 50,000/μL, compared to those above, undergoing dental interventions. Methods Quantitative synthesis without meta‐analysis was conducted through an electronic search conducted on Ovid MEDLINE and Embase from 1946 to ...
Guang Xu David Lim +3 more
wiley +1 more source
ABSTRACT Objectives To evaluate the real‐world effectiveness of octocog alfa (BAY 81‐8973; Kovaltry) in people with haemophilia A (PwHA), including under‐represented subgroups. Methods We retrospectively analysed the American Thrombosis and Hemostasis Network (ATHN) dataset to identify the characteristics, treatment/clinical histories and annualised ...
Martin Chandler +4 more
wiley +1 more source
Management of pregnancy and childbirth in Glanzmann thrombasthenia: A case series and review
To illustrate the challenges in the management of women with Glanzmann thrombasthenia (GT) planning a pregnancy, we conducted a literature review and present a case series of eight women giving detailed descriptions of reproductive health problems, platelet alloimmunisation, treatment to prevent post‐partum haemorrhage and neonatal outcomes.
Karlijn H. G. Rutten +9 more
wiley +1 more source
Delayed onset of brain edema and mislocalization of aquaporin-4 in dystrophin-null transgenic mice [PDF]
Cerebral water accumulation was studied during induction of brain edema in dystrophin-null transgenic mice (mdx-βgeo) and control mice. Immunofluorescence and immunoelectron microscopic analyses of dystrophin-null brains revealed a dramatic reduction of ...
Sulyok, E. +10 more
core
Vasopressin‐Sensitive Aqp2 Regulation Mediated by the TAZ‐NR4A1 Axis in Renal Collecting Duct Cells
The TAZ‐NR4A1 axis was identified as a critical regulator of vasopressin‐induced AQP2 expression, essential for water homeostasis. Conditional TAZ‐knockout mice showed polyuria and a significant decrease in AQP2 expression in collecting ducts. In mpkCCDc11 cells, TAZ knockdown significantly impaired vasopressin‐mediated AQP2 expression independently of
Hong Seok Choi +6 more
wiley +1 more source

