Platelet Levels Associated With Bleeding Risk for Dental Interventions: A Systematic Review
ABSTRACT Objectives To evaluate evidence in relation to postoperative bleeding in humans aged ≥ 16 with preoperative platelet counts < 50,000/μL, compared to those above, undergoing dental interventions. Methods Quantitative synthesis without meta‐analysis was conducted through an electronic search conducted on Ovid MEDLINE and Embase from 1946 to ...
Guang Xu David Lim +3 more
wiley +1 more source
An extracellular residue determines the agonist specificity of V2 vasopressin receptors [PDF]
The specific V2 agonist 1-deamino [8-d-arginine]-vasopressin (dDAVP), used for treatment of central diabetes insipidus, binds to vasopressin V2 receptors from human, bovine and rat kidney with an affinity that is similar to that of the natural hormone ...
Gorbulev, V. +11 more
core +1 more source
ABSTRACT Objectives Acquired Hemophilia A (AHA) is a rare, potentially life‐threatening bleeding disorder caused by autoantibodies against factor VIII (FVIII). We aimed to characterize patients with AHA in Nova Scotia, Canada, and assess diagnostic delays.
Rachelle Blackman +4 more
wiley +1 more source
[7-Glycine]deamino-1-carba-vasopressin: Synthesis and pharmacological properties
[8-Arginine]deamino-1-carba-vasopressin and its 7-glycine derivative were prepared by condensation of the amino-terminal, cyclic part of the molecule with carboxy-terminal tripeptide amides.
Tomislav Barth +2 more
core +1 more source
ABSTRACT Objectives To evaluate the real‐world effectiveness of octocog alfa (BAY 81‐8973; Kovaltry) in people with haemophilia A (PwHA), including under‐represented subgroups. Methods We retrospectively analysed the American Thrombosis and Hemostasis Network (ATHN) dataset to identify the characteristics, treatment/clinical histories and annualised ...
Martin Chandler +4 more
wiley +1 more source
Copeptin levels remain unchanged during the menstrual cycle [PDF]
Copeptin, a surrogate marker for arginin vasopressin production, is evaluated as an osmo-dependent stress and inflammatory biomarker in different diseases.
Christian Schindler (71594) +23 more
core +1 more source
Desmopressin (DDAVP): indications and practicalities
BACKGROUND: Desmopressin (1-deamino-8-D-arginine vasopressin, or DDAVP) is available in Switzerland for the treatment of non-severe haemophilia A and von Willebrand disease.
Eugenia Biguzzi +9 more
doaj +1 more source
Management of pregnancy and childbirth in Glanzmann thrombasthenia: A case series and review
To illustrate the challenges in the management of women with Glanzmann thrombasthenia (GT) planning a pregnancy, we conducted a literature review and present a case series of eight women giving detailed descriptions of reproductive health problems, platelet alloimmunisation, treatment to prevent post‐partum haemorrhage and neonatal outcomes.
Karlijn H. G. Rutten +9 more
wiley +1 more source
Preparation of oxytocin, arginine-vasopressin and its deamino-analogue serves as an example of use of 2,4,6-trimethylbenzyl group for protection of the cysteine sulfur atom in the peptide synthesis. This modified benzyl group is sufficiently stable under
Tomislav Barth +3 more
core +1 more source
Oxytocin at physiological concentrations evokes adrenocorticotropin (ACTH) release from corticotrophs by increasing intracellular free calcium mobilized mainly from intracellular stores. Oxytocin displays synergistic or additive effects on ACTH-releasing factor or arginine vasopressin-induced ACTH secretion, respectively [PDF]
The potency of oxytocin (OT) in evoking ACTH secretion by isolated, superfused rat adenohypophyseal corticotrophs and its enhancement by CRF and arginine vasopressin (AVP) were analyzed.
Link, H. +3 more
core +1 more source

