Results 41 to 50 of about 1,266 (156)

Outcomes of Dental Treatment Procedures in People With Haemophilia Treated Under a Comprehensive Care Model: An Analysis of Cases From a Tertiary Care Centre

open access: yesHaemophilia, Volume 31, Issue 4, Page 617-624, July 2025.
ABSTRACT Background Haemophilia is a chronic, lifelong bleeding disorder that requires interdisciplinary care to manage and mitigate the disease burden throughout a patient's life. There is no universally accepted protocol for managing haemophilia patients during dental care.
Mathangi Kumar   +6 more
wiley   +1 more source

Use of a Modified Transhepatic Rendezvous Technique for Stenting of Malignant Biliary Obstruction in 2 Cats

open access: yesJournal of Veterinary Internal Medicine, Volume 39, Issue 4, July/August 2025.
ABSTRACT We describe the successful treatment of biliary duct obstruction (BDO) secondary to biliary carcinoma involving the bile duct, cystic duct, and intrahepatic ducts in two adult domestic shorthair cats using a novel technique. Both cats presented with marked hyperbilirubinemia, increased liver enzyme activities, and ultrasonographic evidence of ...
Robin Doherty   +2 more
wiley   +1 more source

Hermansky‐Pudlak Syndrome: From Molecular Pathogenesis to Targeted Therapies

open access: yesIUBMB Life, Volume 77, Issue 5, May 2025.
ABSTRACT Hermansky‐Pudlak syndrome (HPS) is a rare inherited disorder caused by defects in lysosome‐related organelles (LROs) in various tissues, including platelets, melanocytes, and endothelial cells. Key features of HPS include oculocutaneous albinism, bleeding tendency, and, in some cases, pulmonary fibrosis, granulomatous colitis, and ...
Francesca Tondi   +6 more
wiley   +1 more source

Acute Compartment Syndrome in Congenital and Acquired Haemophilia

open access: yesHaemophilia, Volume 31, Issue 3, Page 373-390, May 2025.
ABSTRACT Background Acute compartment syndrome (ACS) is a surgical emergency defined as an increase in intramuscular pressure within a compartment that compromises capillary perfusion and threatens the survival of compartment tissues. A sustained increase in compartment pressure causes irreversible necrosis of nerves and muscles, leading to permanent ...
Emerito Carlos Rodriguez‐Merchan   +2 more
wiley   +1 more source

Association of Anaesthetists guidelines: the use of blood components and their alternatives

open access: yesAnaesthesia, Volume 80, Issue 4, Page 425-447, April 2025.
Summary Background The administration of blood components and their alternatives can be lifesaving. Anaemia, bleeding and transfusion are all associated with poor peri‐operative outcomes. Considerable changes in the approaches to optimal use of blood components and their alternatives, driven by the findings of large randomised controlled trials and ...
Akshay Shah   +12 more
wiley   +1 more source

Autonomic nervous system dysregulation in children with monosymptomatic nocturnal enuresis

open access: yesActa Paediatrica, Volume 113, Issue 10, Page 2288-2296, October 2024.
Abstract Aim To investigate the role of autonomic nervous system in subpopulations of children with enuresis. Methods We included 35 children with enuresis, divided in children with (17) and without nocturnal polyuria (18) and 43 healthy controls. For all participants hormones and neurotransmitters were measured.
Maria Angeli   +7 more
wiley   +1 more source

Identification of protein kinase A signalling molecules in renal collecting ducts

open access: yesThe Journal of Physiology, Volume 602, Issue 13, Page 3057-3067, 1 July 2024.
Abstract figure legend Each A‐kinase anchoring protein (AKAP) separates protein kinase A (PKA) into specific compartments, such as the mitochondria, nucleus or intracellular vesicles, facilitating spatially restricted cAMP/PKA signalling to increase the specificity of the PKA substrate.
Fumiaki Ando, Yu Hara, Shinichi Uchida
wiley   +1 more source

Safety and efficacy of desmopressin (DDAVP) in preventing hematoma expansion in intracranial hemorrhage associated with antiplatelet drugs use: A systematic review and metaanalysis

open access: yesBrain and Behavior, Volume 14, Issue 5, May 2024.
Abstract Introduction One of the most serious complications associated with antiplatelet agents is antiplatelet‐associated intracranial hemorrhage (AA‐ICH). Desmopressin is a synthetic antidiuretic hormone (ADH) analog. It has been linked to improving patient outcomes in antiplatelet‐induced intracranial hemorrhage.
Faizan Shahzad   +10 more
wiley   +1 more source

Serum sodium level fluctuations following the resection of childhood‐onset craniopharyngioma

open access: yesBrain and Behavior, Volume 14, Issue 3, March 2024.
Serum sodium levels after craniopharyngioma resection showed a triphasic pattern in most cases. The risk of postoperative hyponatremia varied depending on preoperative endocrine hormone deficiency, tumor status (primary or recurrent), and surgical approach.
Yuqi Miao   +11 more
wiley   +1 more source

Acquired von Willebrand syndrome in a patient with monoclonal gammopathy of unknown significance: A case report

open access: yesClinical Case Reports, Volume 12, Issue 2, February 2024.
Abstract Monoclonal gammopathy of uncertain significance associated acquired von Willebrand syndrome is a serious bleeding condition driven by immunological clearance of von Willebrand factor and has limited treatment options. We present a patient who achieved durable remission through eradication of the monoclonal paraprotein with clonal directed ...
Garima Gupta   +3 more
wiley   +1 more source

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