Results 51 to 60 of about 106,855 (202)
JUSTIFICATIVA E OBJETIVOS: Os pacientes portadores da doença de von Willebrand apresentam sangramento anormal após ferimentos e procedimentos cirúrgicos, já que esta afeta a hemostasia primária e secundária devido à alteração do fator VIII.
Roberto Martins Matos Junior +4 more
doaj +1 more source
Vasopressin‐Sensitive Aqp2 Regulation Mediated by the TAZ‐NR4A1 Axis in Renal Collecting Duct Cells
The TAZ‐NR4A1 axis was identified as a critical regulator of vasopressin‐induced AQP2 expression, essential for water homeostasis. Conditional TAZ‐knockout mice showed polyuria and a significant decrease in AQP2 expression in collecting ducts. In mpkCCDc11 cells, TAZ knockdown significantly impaired vasopressin‐mediated AQP2 expression independently of
Hong Seok Choi +6 more
wiley +1 more source
ABSTRACT Background Haemophilia is a chronic, lifelong bleeding disorder that requires interdisciplinary care to manage and mitigate the disease burden throughout a patient's life. There is no universally accepted protocol for managing haemophilia patients during dental care.
Mathangi Kumar +6 more
wiley +1 more source
Female sheep were used to assay antihaemophilic (factor VIII enhancing) activity of arginine vasopressin, deamino-(D-arginine8)-vasopressin (DDAVP) and adrenaline.
Rösli R +4 more
core +1 more source
ABSTRACT We describe the successful treatment of biliary duct obstruction (BDO) secondary to biliary carcinoma involving the bile duct, cystic duct, and intrahepatic ducts in two adult domestic shorthair cats using a novel technique. Both cats presented with marked hyperbilirubinemia, increased liver enzyme activities, and ultrasonographic evidence of ...
Robin Doherty +2 more
wiley +1 more source
DDAVP (desmopressin; 1‐deamino‐cys‐8‐
We tested the response to desmopressin (1‐deamino‐cys‐8‐d‐arginine‐vasopressin; DDAVP) in four patients with haemophilia B [factor IX (F IX) at diagnosis 1·4–5%]. The activated partial thromboplastin time (aPTT) was significantly shortened in all patients.
Ehl, Stephan +2 more
openaire +3 more sources
Hermansky‐Pudlak Syndrome: From Molecular Pathogenesis to Targeted Therapies
ABSTRACT Hermansky‐Pudlak syndrome (HPS) is a rare inherited disorder caused by defects in lysosome‐related organelles (LROs) in various tissues, including platelets, melanocytes, and endothelial cells. Key features of HPS include oculocutaneous albinism, bleeding tendency, and, in some cases, pulmonary fibrosis, granulomatous colitis, and ...
Francesca Tondi +6 more
wiley +1 more source
The molecular basis of V2 vasopressin receptor-G Protein coupling selectivity [PDF]
GProteingekoppelte Rezeptoren (GPCRs) stellen eine der größten in der Natur vorkommenden Proteinfamilien dar (Watson and Arkinstall, 1994). GPCRs sind plasmamembranständige Proteine, die mit heterotrimären GProteinen interagieren und eine Vielzahl an ...
Erlenbach, Isolde
core
Maximum urine concentration capacity was studied in healthy adults using different routes and doses of administration of 1-deamino-8-d-arginine vasopressin (DDAVP) - desmopressin.
Harris, Alan +4 more
core +1 more source
Acute Compartment Syndrome in Congenital and Acquired Haemophilia
ABSTRACT Background Acute compartment syndrome (ACS) is a surgical emergency defined as an increase in intramuscular pressure within a compartment that compromises capillary perfusion and threatens the survival of compartment tissues. A sustained increase in compartment pressure causes irreversible necrosis of nerves and muscles, leading to permanent ...
Emerito Carlos Rodriguez‐Merchan +2 more
wiley +1 more source

