Results 21 to 30 of about 2,272 (238)

Preclinical efficacy of [V 4 Q 5 ]dDAVP, a second generation vasopressin analog, on metastatic spread and tumor-associated angiogenesis in colorectal cancer [PDF]

, 2018
Purpose Control of metastatic spread of colorectal cancer (CRC) remains as a major therapeutic challenge. [V 4 Q 5 ]dDAVP is a vasopressin peptide analog with previously reported anticancer activity against carcinoma tumors.
Alonso, Daniel Fernando, Garona, Juan, Gomez, Daniel Eduardo, Pifano, Marina, Ripoll, Giselle Vanina, Segatori, Valeria Inés, Sobol, Natasha Tatiana   +6 more
core   +1 more source

Desmopressin (DDAVP) use in patients with von Willebrand disease: A single‐centre retrospective review of test response and clinical outcomes

Haemophilia, Volume 29, Issue 4, Page 1095-1103, July 2023., 2023
Abstract Introduction Peri‐procedural management of von Willebrand disease (VWD) utilizes von Willebrand factor (VWF) concentrates or desmopressin (DDAVP) to increase VWF levels. DDAVP is safe, easily administered, and inexpensive. Currently, a consensus definition for adequate DDAVP response is lacking, and outcomes of peri‐procedural DDAVP use in VWD
Priya Chandrakumaran, Julia Hews‐Girard, Man‐Chiu Poon   +2 more
wiley   +1 more source

Management of pregnancy and childbirth in Glanzmann thrombasthenia: A case series and review. [PDF]

Br J Haematol
To illustrate the challenges in the management of women with Glanzmann thrombasthenia (GT) planning a pregnancy, we conducted a literature review and present a case series of eight women giving detailed descriptions of reproductive health problems, platelet alloimmunisation, treatment to prevent post‐partum haemorrhage and neonatal outcomes.
Rutten KHG, Tsiamita O, Van Thillo Q, Raheja P, Kaler M, van Galen KPM, Hogg M, Bowles L, Schutgens REG, Sivapalaratnam S.   +9 more
europepmc   +2 more sources

Vasopressin regulates the growth of the biliary epithelium in polycystic liver disease [PDF]

, 2016
The neurohypophysial hormone arginine vasopressin (AVP) acts by three distinct receptor subtypes: V1a, V1b, and V2. In the liver, AVP is involved in ureogenesis, glycogenolysis, neoglucogenesis and regeneration. No data exist about the presence of AVP in
Alpini, Gianfranco, Carpino, Guido, Franchitto, Antonio, Gaudio, Eugenio, Glaser, Shannon, Mancinelli, Romina, Olivero, Francesca, Onori, Paolo, Pannarale, Luigi, Sferra, Roberta, Venter, Julie, Vetuschi, Antonella   +11 more
core   +1 more source

Depression and anxiety in persons with Von Willebrand disease

Haemophilia, Volume 29, Issue 2, Page 545-554, March 2023., 2023
Abstract Objective We assessed sociodemographic and clinical characteristics associated with depression and anxiety in individuals with Von Willebrand disease (VWD) aged ≥12 years. Methods The study collected data on patients’ sociodemographic, joint problems and health‐related quality of life (HRQoL) using EQ‐5D‐3L, 8‐item patient health questionnaire
Jonathan C. Roberts, Roshni Kulkarni, Peter A. Kouides, Robert F. Sidonio Jr., Shannon L. Carpenter, Barbara A. Konkle, Joanne Wu, Megan M. Ullman, Randall Curtis, Judith R. Baker, Nicole Crook, Michael B. Nichol   +11 more
wiley   +1 more source

Practical management of nocturia in urology

Indian Journal of Urology, 2008
Until last decades, nocturia has been considered as an irritative symptom of benign prostatic hyperplasia (BPH), but the nocturia is unresponsive symptoms to various modalities of BPH treatment.
Myeong Heon Jin, Du Geon Moon
doaj   +1 more source

Synthetic Vasopressin and Oxytocin Analogs and Their Potential Use in Hemorrhagic, Traumatic and Septic Shock: A Personal Perspective [PDF]

, 2017
As one of us has stated many years ago, “shock is a significant and sustained loss of effective circulating blood volume. It will eventuate in hypoperfusion of critical peripheral tissues, thus leading to a deficit in transcapillary exchange function in ...
Altura BM, Carella A, Gebrewold A, Altura BT   +3 more
core   +1 more source

Genetic deletion of the nuclear factor of activated T cells 5 in collecting duct principal cells causes nephrogenic diabetes insipidus

The FASEB Journal, Volume 36, Issue 11, November 2022., 2022
Abstract Water homeostasis is tightly regulated by the kidneys via the process of urine concentration. During reduced water intake, the antidiuretic hormone arginine vasopressin (AVP) binds to the vasopressin receptor type II (V2R) in the kidney to enhance countercurrent multiplication and medullary osmolality, and increase water reabsorption via ...
Federica Petrillo, Dmitry Chernyakov, Cristina Esteva‐Font, Søren B. Poulsen, Bayram Edemir, Robert A. Fenton   +5 more
wiley   +1 more source

Does Desmopressin Reduce Intraoperative Bleeding in Patients Who Undergo Nasal Surgery? A Systematic Review and Meta-Analysis [PDF]

Journal of Rhinology
Background and Objectives This study aimed to determine the efficacy of prophylactic desmopressin administered via the intranasal or intravenous route in reducing intraoperative bleeding during nasal surgery.
Sun Hong Kim, Ah Young Bae, Do Hyun Kim, Se Hwan Hwang   +3 more
doaj   +1 more source

PFA-100 test in the detection of platelet dysfunction and monitoring DDAVP in a patient with liver cirrhosis undergoing inguinal hernia repair [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2012
Introduction. Hemostatic abnormalities in liver cirrhosis are complex and multifactorial and may predispose to prolonged hemorrhage following invasive procedures.
Vučelić Dragica, Golubović Milka, Bjelović Miloš   +2 more
doaj   +1 more source