Results 71 to 80 of about 12,800 (198)

Perioperative Management in Persons With Haemophilia on Rebalancing Therapies: A Narrative Review

Haemophilia, EarlyView.
ABSTRACT Introduction Perioperative management in haemophilia often requires on‐demand use of clotting factor concentrates (CFC) and/or bypassing agents. Rebalancing agents (fitusiran, concizumab, marstacimab) offer a novel approach to prophylaxis by modulating endogenous anticoagulant pathways to restore haemostatic balance.
Amanda M. Henderson, Roy Khalife, Kelsey Uminski   +2 more
wiley   +1 more source

Development of formulations of desmopressin intranasal drops [PDF]

, 2002
In recent years synthetic vasopressin analogues (particularly desmopressin) emerged as safe and effective representatives of this class of drugs for same clinical indications as natural hormone.
Savickas, Arūnas, Maciulevičius, Jonas, Gerbutavičienė, Rima Jūratė, Klimas, Rimantas   +3 more
core  

The Rate of Relapse of Primary Monosymptomatic Nocturnal Enuresis with Desmopressin Treatment in Comparison with Combined Treatment of Desmopressin and Tolterodine in Children Aged 5 to 16 Years [PDF]

Iranian South Medical Journal
Background: In the process of treating children with primary monosymptomatic nocturnal enuresis (PMNE), the relapse of PMNE after stopping the medicine causes the child to take the medicine for a prolonged time.
Fereshteh Sobhani, Banafsheh Arad, Abolfazl Mahyar, Ameneh Barikani   +3 more
doaj  

A comparative study of intranasal desmopressin and intranasal ketamine for pain management in renal colic patients: a randomized double-blind clinical trial [PDF]

Clinical and Experimental Emergency Medicine
Objective Urolithiasis is one of the most common urological diseases worldwide, usually presenting as renal colic that leads to severe pain that requires analgesic treatment.
Farhad Heydari, Reza Azizkhani, Saeed Majidinejad, Majid Zamani, Aref Norouzian   +4 more
doaj   +1 more source

100 Years of von Willebrand Disease (VWD): Comparison of Historical and Contemporary von Willebrand Factor (VWF) Activity Assays in the Laboratory Identification of VWD

Haemophilia, EarlyView.
Abstract Introduction von Willebrand disease (VWD) is a prevalent bleeding disorder resulting from deficiencies and/or defects in von Willebrand factor (VWF). Accurately diagnosing VWD, particularly distinguishing between qualitative defects (types 2A, 2B, 2 M, and 2N) and quantitative defects (types 1 and 3), poses challenges that have significant ...
Emmanuel J. Favaloro, Sandya Arunachalam, Mahzuza Salwa, Ronny Vong, Leonardo Pasalic   +4 more
wiley   +1 more source

Desmopressin Administration and Impact on Hypertonic Saline Effectiveness in Intracranial Hemorrhage.

, 2021
INTRODUCTION: Desmopressin improves hemostasis through the release of factor VIII, von Willebrand factor, and tissue plasminogen activator, and increases platelet adhesion.
Bromberg, William, Bowers, Emily G, Johnson, Audrey, Shaw, Eric   +3 more
core   +1 more source

Protective effects of Desmopressin acetate on retention of spatial memory deficits induced by post-traumatic stress disorder in Rats

مجله دانشگاه علوم پزشکی گرگان, 2012
Background and Objective: Post-traumatic stress disorder (PTSD) impairs spatial learning and memory. Desmopressin acetate ameliorates the cognitive deficits induced by electroconvulsive shock. This study was designed to evaluate the protective effects of
Mehrabadi S, Makvand Hosseini Sh, Miladi Gorji H, Nikfarjam Haft Asia M   +3 more
doaj  

How I Investigate Bleeding Disorders of Unknown Cause: Current Diagnostic Pathways and Gaps in Laboratory Investigation

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Bleeding disorder of unknown cause (BDUC) constitutes the largest group of patients presenting with a mild‐to‐moderate bleeding tendency in tertiary care settings. Their clinical bleeding phenotype is characterized by mucocutaneous bleeding, as well as bleeding following surgical challenges or childbirth, and is associated with impaired health‐
Dino Mehic, Faris Karaselimovic, Tim Dreier, Johanna Gebhart   +3 more
wiley   +1 more source

Immune proteomic associations with indices of cortical development in 5‐year‐old children

Journal of Anatomy, EarlyView.
Typically developing 5‐year‐old children (n = 101–126) from the FinnBrain Birth Cohort Study, Finland, underwent both targeted serum immune proteomics and magnetic resonance brain imaging. Multiple inflammatory markers, from one cluster of co‐expressed immune proteins, were negatively associated with indices of cortical development, including thickness,
Aaron Barron, Aylin Rosberg, Jetro J. Tuulari, Minna Lukkarinen, Harri Merisaari, Eero Silver, Venla Kumpulainen, Anni Copeland, Ekaterina Saukko, Alex M. Dickens, Matej Oresic, Tuulia Hyötylainen, Linnea Karlsson, Hasse Karlsson, Isabella L. C. Mariani Wigley, Elmo P. Pulli   +15 more
wiley   +1 more source

Hypothalamic Neurochemical and Microglial Suppression in Long‐Standing Human Hibernation‐Like Syndrome

Neuropathology and Applied Neurobiology, Volume 52, Issue 6, December 2026.
A rare case of a human hibernation‐like syndrome was associated with preserved hypothalamic anatomy but profound suppression of neuroendocrine and circadian neuropeptide systems. Marked reductions in synaptic and microglial immunoreactivity suggest a suppressed hypothalamic neuron–glial network, despite preserved astrocytic markers, myelination and ...
Wei Jiang, Andries Kalsbeek, Roelof A. Hut, Dick F. Swaab, Chun‐Xia Yi   +4 more
wiley   +1 more source