Results 41 to 50 of about 15,363 (165)

The clinical use of platelet transfusions: A systematic literature review and meta‐analysis on behalf of the International Collaboration for Transfusion Medicine Guidelines

open access: yesTransfusion, EarlyView.
Abstract Background Platelets are frequently transfused, but supply and potential harms highlight the importance of appropriate use. Study Design and Methods Our systematic review (SR) followed a predefined protocol. Eligible studies included SRs, randomized controlled trials (RCTs), and matched cohort observational studies between 1946 and March 2025.
Rachel Jug   +7 more
wiley   +1 more source

Pregnancy and delivery outcomes in individuals with RUNX1‐Familial Platelet Disorder

open access: yes
British Journal of Haematology, EarlyView.
Natalie T. Deuitch   +8 more
wiley   +1 more source

Coagulopathy as a Complication of Cardiopulmonary Arrest Following Balloon Valvuloplasty in a Dog

open access: yesVeterinary Medicine and Science, Volume 11, Issue 4, July 2025.
An 8‐month‐old dog developed a consumptive coagulopathy and presumptive DIC following cardiac arrest during a balloon valvuloplasty procedure. Successful management required massive transfusion therapy and critical care. ABSTRACT Objective To describe successful management of a coagulopathy secondary to cardiopulmonary arrest (CPA) associated with ...
Marissa A. Turner, Theresa C. Hallowell
wiley   +1 more source

Langerhans Cell Histiocytosis With MAP2K1E102_I103del Mutation Successfully Treated With Trametinib

open access: yeseJHaem, Volume 6, Issue 3, June 2025.
ABSTRACT The discovery of the MAPK pathway mutations in lesions of patients with Langerhans cell histiocytosis (LCH) has made targeted therapy an important therapeutic approach for these patients. Theoretically, the RAF‐independent mutation MAP2K1E102_I103del is naturally resistant to allosteric MEK inhibitors.
Min Lang, Long Chang, Xin‐xin Cao
wiley   +1 more source

Nocturia: A Nonspecific but Bothersome Symptom in Urology [PDF]

open access: yes, 2011
Nocturia is a common symptom in both men and women. It can be troublesome by itself by disturbing sleep and can have a significant impact on the quality of sleep and the quality of life. In men, nocturia is often ascribed to prostatic disease without due
Chen, Sung-Lang
core   +1 more source

Imaging Assessment of the Pituitary Gland and Long‐Term Endocrinological Abnormalities in Pediatric Brain Cancer Survivors

open access: yesJournal of Magnetic Resonance Imaging, Volume 61, Issue 6, Page 2516-2522, June 2025.
Background Pediatric brain cancer survivors often experience hypothalamic–pituitary dysfunction due to cranial irradiation and chemotherapy. While hormone deficiencies have been studied, the changes in pituitary size and shape on long‐term MRI and their relationship to endocrine dysfunction remain under‐explored.
Feras Qawasmi   +8 more
wiley   +1 more source

Treatment of Bleeding Episodes With Efanesoctocog Alfa in Previously Treated Patients With Severe Hemophilia A in the Phase 3 XTEND‐1 Study

open access: yesAmerican Journal of Hematology, Volume 100, Issue 5, Page 813-820, May 2025.
ABSTRACT Despite therapeutic advances, people with hemophilia experience bleeds. These may be life‐threatening, result in permanent joint damage, chronic pain, difficulties with mobility/daily activities, and impact quality of life. In the XTEND‐1 study (NCT04161495), once‐weekly efanesoctocog alfa (50 IU/kg) prophylaxis provided highly effective bleed
Angela C. Weyand   +7 more
wiley   +1 more source

Recent advances in managing and understanding enuresis [PDF]

open access: yes, 2017
Enuresis, particularly in children during sleep, can be a debilitating condition, affecting the quality of life of the child and his or her family. The pathophysiology of nocturnal enuresis, though not clear, revolves around the inter-related mechanisms ...
Dhondt, Karlien   +3 more
core   +3 more sources

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