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Combined oral contraceptives alter ectonucleotidase and adenosine deaminase activities in peripheral blood cells. [PDF]
Moreschi BP +4 more
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Acute ST elevation myocardial infarction in a young female patient without cardiovascular risk factors-Massive left main coronary artery thrombosis induced by oral contraceptive pills: a case report. [PDF]
Younes S +7 more
europepmc +1 more source
Non-Invasive Diagnosis of Endometriosis by Questionnaires in Patients Using Contraception. [PDF]
Zeppernick F +10 more
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Pharmacokinetics of desogestrel
American Journal of Obstetrics and Gynecology, 1993A synthetic form of desogestrel, a gonane progestin, was developed because desogestrel's enhanced selectivity eliminates adverse, androgen-dependent, metabolic effects at contraceptive doses. Desogestrel is rapidly and completely metabolized in the liver and gut wall to 3-keto-desogestrel, which is the active metabolite mediating the progestin effects.
Eli Y Adashi
exaly +3 more sources
Clinical Obstetrics and Gynecology, 1995
Desogestrel is a new, potent progestogen with very low androgenic properties. When used as a contraceptive, it is a strong antiovulatory compound, even at low doses. The clinical efficacy is as good as that of the old progestogens. It has a low incidence of side effects and complications, similar to other progestogens.
openaire +2 more sources
Desogestrel is a new, potent progestogen with very low androgenic properties. When used as a contraceptive, it is a strong antiovulatory compound, even at low doses. The clinical efficacy is as good as that of the old progestogens. It has a low incidence of side effects and complications, similar to other progestogens.
openaire +2 more sources
Selectivity information on desogestrel
American Journal of Obstetrics and Gynecology, 1993Improvement in oral contraceptive formulations was originally achieved through dose reduction of the estrogen and progestogen components. Recently, further improvement was achieved by increasing the selectivity of contraceptive progestins. The ratio between the affinity for the progesterone receptor and the affinity for the androgen receptor is an ...
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Serum levels of 3-keto-desogestrel after oral administration of desogestrel and 3-keto-desogestrel
Contraception, 1986In a cross-over study with orally administered desogestrel (0.150 mg) plus ethinyloestradiol (0.030 mg) and 3-keto-desogestrel (0.150 mg) plus ethinyloestradiol (0.030 mg) in ten women under steady-state conditions, the serum levels of 3-keto-desogestrel were monitored by radioimmunoassay.
H G, Hasenack, A M, Bosch, K, Käär
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