Results 61 to 70 of about 21,269 (216)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Luxury consumption in tourism: the case of Dubai – Part 2
2016 was a year of critical discussion and reflection for Nadkarni and Heyes as they considered the luxury image of Dubai in this journal. Discussions outlined the theoretical nature of luxury while also addressing the current hotel industry statistics ...
Andy Heyes, Sanjay Nadkarni
doaj +1 more source
Transport and infrastructural basis of the tourism development strategy in the Arkhangelsk Oblast
The article, devoted to the analysis of transport and geographical locations, describes possible strategies for the development of tourism in the Arkhangelsk Oblast.
TSVETKOV A.Yu.
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
The manner how to increase the revenues in tourism, is the question that can be answerd on different ways. One of the ways that may contribute that is the interaction and conditionality of hotel business and maritime tourism.
Kaluđerović Marija
doaj +1 more source
In the current context of reconfiguration and increased competition between regions, many destinations are attempting to stand out by organizing high-profile events whose objective is to enhance their region’s reputation. From an analytical point of view,
Olivier Bessy
doaj +1 more source
Generally speaking, destination choice represents an optimization problem, where every agent searches for his or her optimal destination according to an objective function, subject to various constraints such as the agent’s travel time budget – as well as interactions with other agents – while competing for space-time slots in the infrastructure.
Horni, Andreas +2 more
openaire +2 more sources
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
The relationship between tourist satisfaction and posttravel behaviour: Evidence from international tourists visiting Ethiopia [PDF]
The satisfactions and memorable experience of visitors is a result of both quality service and unique destination attributes. The aim of this research was to study the relationship between tourist satisfaction and post travel behaviour.
Kassegn Berhanu, Prof. Dr. Sahil Raj
doaj

