Results 61 to 70 of about 21,269 (216)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Luxury consumption in tourism: the case of Dubai – Part 2

open access: yesResearch in Hospitality Management, 2020
2016 was a year of critical discussion and reflection for Nadkarni and Heyes as they considered the luxury image of Dubai in this journal. Discussions outlined the theoretical nature of luxury while also addressing the current hotel industry statistics ...
Andy Heyes, Sanjay Nadkarni
doaj   +1 more source

Transport and infrastructural basis of the tourism development strategy in the Arkhangelsk Oblast

open access: yesАрктика и Север, 2020
The article, devoted to the analysis of transport and geographical locations, describes possible strategies for the development of tourism in the Arkhangelsk Oblast.
TSVETKOV A.Yu.
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Interaction and Conditionality of Hotel Business and Maritime Tourism, as a Significant Factor in Increasing Revenues in Tourism

open access: yesECONOMICS, 2019
The manner how to increase the revenues in tourism, is the question that can be answerd on different ways. One of the ways that may contribute that is the interaction and conditionality of hotel business and maritime tourism.
Kaluđerović Marija
doaj   +1 more source

Innovations événementielles et structuration des destinations touristiques. Pour une hybridation des approches : l’exemple de l’Ultra-Trail du Mont-Blanc

open access: yesMondes du Tourisme, 2016
In the current context of reconfiguration and increased competition between regions, many destinations are attempting to stand out by organizing high-profile events whose objective is to enhance their region’s reputation. From an analytical point of view,
Olivier Bessy
doaj   +1 more source

Destination Innovation

open access: yes, 2016
Generally speaking, destination choice represents an optimization problem, where every agent searches for his or her optimal destination according to an objective function, subject to various constraints such as the agent’s travel time budget – as well as interactions with other agents – while competing for space-time slots in the infrastructure.
Horni, Andreas   +2 more
openaire   +2 more sources

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

The relationship between tourist satisfaction and posttravel behaviour: Evidence from international tourists visiting Ethiopia [PDF]

open access: yesAfrican Journal of Hospitality, Tourism and Leisure, 2020
The satisfactions and memorable experience of visitors is a result of both quality service and unique destination attributes. The aim of this research was to study the relationship between tourist satisfaction and post travel behaviour.
Kassegn Berhanu, Prof. Dr. Sahil Raj
doaj  

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