Results 81 to 90 of about 302,461 (314)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Competitiveness of Slovenia as a Tourist Destination [PDF]

open access: yes
In an increasingly saturated market the fundamental task for the destination management, is understanding how tourism destination competitiveness can be enhanced and sustained.
Doris Gomezelj Omerzel
core  

An Analysis of the Demand for Tourist Accommodation to Travel with Dogs in Spain

open access: yesSocieties
Pets, generally, and dogs have become an essential part of families. This situation implies that people consider their dogs when planning family holidays, excluding moving to a second home.
José E. Ramos-Ruiz   +3 more
doaj   +1 more source

Aspects of the Revelation of the Divine in St. Gregory Palamas’ Treatise De Operationibus Divinis

open access: yesPerichoresis: The Theological Journal of Emanuel University, 2019
In this paper, we examine the concepts ‘destination’, ‘revelation’, ‘foreknowledge’, ‘will’, ‘transmission’, ‘motion’, and ‘grace’, as they appear in Gregory Palamas’ treatise De opera-tionibus divinis.
Terezis Christos, Tempelis Elias
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

2014 St. Gallen Consensus on destination management

open access: yes, 2015
This paper summarizes the main insights of the second Biennial Forum on Advances in Destination Management (ADM), held in St. Gallen (Switzerland). Issues in five domains preoccupied the discourse of scholars and practitioners alike: (1) the definition ...
Beritelli, Pietro,   +2 more
core   +1 more source

The Analysis of the Tourist Circulation Manifested in the Constanta County during 2005 – 2008 [PDF]

open access: yesAnnals of Dunarea de Jos University. Fascicle I : Economics and Applied Informatics, 2009
During 2005 – 2008, the tourist circulation in Constanta County is characterizedby a slight evolution of the tourists’ number, tourists arrived in this area andtheir overnight stays in the tourist reception structures with housing functions.Although this
Daniela Simona NENCIU, Mirela SECARĂ
doaj  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

The Influence of Previous Visitation on Customer's Evaluation of a Tourism Destination [PDF]

open access: yes
The paper investigates the customer's perspective on a tourism destination brand through four proposed dimensions: awareness, image, quality and loyalty dimension.
Maja Konecnik, Mitja Ruzzier
core  

Tiktok made me book it: The impact of Tiktok on tourism destination selection of generation Z and millennials in Manila

open access: yesJournal of Hospitality, Tourism & Cultural Research
The advent of social media, with TikTok at the forefront, has transformed the way individuals access information and make decisions, particularly in the context of tourism destination selection.
Sydney Monic U. Alejo   +5 more
doaj   +1 more source

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