Results 41 to 50 of about 121,411 (267)

Re-modelling Muslim-friendly tourism value chain ecosystem: the case study of West Sumatera, Indonesia

open access: yesCogent Social Sciences
The development of Muslim-friendly tourism destinations is an effort to differentiate products and the tourism market amidst the aggressive growth of global tourism.
Anang Sutono   +4 more
doaj   +1 more source

ROLE OF SOCIAL MEDIA AS A CATALYST FOR SUSTAINABLE TOURISM DEVELOPMENT IN CALABAR METROPOLIS, NIGERIA [PDF]

open access: yesGeo Journal of Tourism and Geosites
This study investigates the role of social media in tourism development in Calabar, Nigeria, emphasizing its influence on image building, destination promotion, and information dissemination.
Ukwetang John OKPA   +14 more
doaj   +1 more source

The impact of climate change on visitor destination selection: A case study of the Central Drakensberg Region in KwaZulu-Natal

open access: yesJàmbá, 2021
Many variables influence visitors’ destination choices, for example, affordability, attractions, health and safety, and expectancies. Amongst the indirect influences in destination choice by tourists, climate change is perhaps the greatest factor because
Nduduzo A. Ngxongo
doaj   +1 more source

Destination loyalty explained through place attachment, destination familiarity and destination image

open access: yesInternational Journal of Tourism Research, 2020
AbstractThis study explores how familiarity and attachment, along with cognitive and affective image explain destination loyalty across visitors with divergent degrees of frequency of visitation (low vs. high). Serbians (n= 401) who have previously visited Greece comprised the sample population for this study and were surveyed using a self‐administered
Dimitrios Stylidis   +3 more
openaire   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Is online learning effective for practice-based tourism courses? A constructive learning approach

open access: yesTourism and Hospitality Management
Purpose – The aim of this paper is to 1) measure the effectiveness of online learning in practise-based tourism courses, 2) identify the factors that influence the effectiveness of online learning and 3) propose strategies to encourage tourism students
Ilham Junaid, Marianna Sigala
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

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