Results 71 to 80 of about 21,269 (216)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

City break as a form of urban tourism

open access: yesZeszyty Naukowe Małopolskiej Wyższej Szkoły Ekonomicznej w Tarnowie, 2020
The aim of this paper is to investigate the attractiveness of city break trips as a form of urban (cognitive) tourism. The study focuses on the following research questions: What factors influence the popularity of city break trips? Which cities are most
Agata Balińska
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

City marketing to city branding: A novel practice in Zimbabwe destination branding. [PDF]

open access: yesAfrican Journal of Hospitality, Tourism and Leisure, 2018
This study was based on understanding the concept of city marketing as a driver towards the achievement of effective city brands. The main aim was to develop a new destination branding perspective that originates from city branding. The study employed a
Dr Farai Chigora   +1 more
doaj  

Aspects of the Revelation of the Divine in St. Gregory Palamas’ Treatise De Operationibus Divinis

open access: yesPerichoresis: The Theological Journal of Emanuel University, 2019
In this paper, we examine the concepts ‘destination’, ‘revelation’, ‘foreknowledge’, ‘will’, ‘transmission’, ‘motion’, and ‘grace’, as they appear in Gregory Palamas’ treatise De opera-tionibus divinis.
Terezis Christos, Tempelis Elias
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

An Analysis of the Demand for Tourist Accommodation to Travel with Dogs in Spain

open access: yesSocieties
Pets, generally, and dogs have become an essential part of families. This situation implies that people consider their dogs when planning family holidays, excluding moving to a second home.
José E. Ramos-Ruiz   +3 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

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