Results 51 to 60 of about 122,383 (265)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Luxury consumption in tourism: the case of Dubai – Part 2
Research in Hospitality Management, 2020 2016 was a year of critical discussion and reflection for Nadkarni and Heyes as they considered the luxury image of Dubai in this journal. Discussions outlined the theoretical nature of luxury while also addressing the current hotel industry statistics ...
Andy Heyes, Sanjay Nadkarni
doaj +1 more source
Transport and infrastructural basis of the tourism development strategy in the Arkhangelsk Oblast
Арктика и Север, 2020 The article, devoted to the analysis of transport and geographical locations, describes possible strategies for the development of tourism in the Arkhangelsk Oblast.
TSVETKOV A.Yu.
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
ECONOMICS, 2019 The manner how to increase the revenues in tourism, is the question that can be answerd on different ways. One of the ways that may contribute that is the interaction and conditionality of hotel business and maritime tourism.
Kaluđerović Marija
doaj +1 more source
Mondes du Tourisme, 2016 In the current context of reconfiguration and increased competition between regions, many destinations are attempting to stand out by organizing high-profile events whose objective is to enhance their region’s reputation. From an analytical point of view,
Olivier Bessy
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
, 2016 Generally speaking, destination choice represents an optimization problem, where every agent searches for his or her optimal destination according to an objective function, subject to various constraints such as the agent’s travel time budget – as well as interactions with other agents – while competing for space-time slots in the infrastructure.
Horni, Andreas +2 more
openaire +2 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source