Results 31 to 40 of about 11,214 (263)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Factors Affecting Malaysia Tourists’ Destination Loyalty Behavior: A Case Study of Hatyai, Thailand
AMAR (Andalas Management Review), 2023 Retaining the loyal visitors to revisit is highly crucial for generating the revenue in tourism destination as well as reducing the marketing expenses, this empirical study has been designed to primarily explore factors that motivate Malaysia tourists ...
chutima wangbenmad
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
An investigation of destination attributes and service quality of tourism in Amhara Region, Ethiopia [PDF]
African Journal of Hospitality, Tourism and Leisure, 2020 The general objective of this study was to examine tourist evaluation of the destination attributes and how these associate with tourists’ satisfaction in Amhara Region, Ethiopia.
Sisay Haile +2 more
doaj
DESTINATION MARKETING TO IMPROVE DOMESTIC TOURISTS’ RETURN INTENTION
International Journal of Applied Sciences in Tourism and Events, 2020 Purpose: This study aims to analyze tourist return intention through destination attribute (attraction, accessibility, and amenities), promotion, and destination image mediated by tourist satisfaction.
Filda Rahmiati, Andrean Winata
doaj +1 more source
Modeling users' satisfaction and visit intention using AI-based chatbots.
PLoS ONE, 2023 AI-based chatbots are an emerging technology disrupting the tourism industry. Although chatbots have received increasing attention, there is little evidence of their impact on tourists' decisions to visit a destination.
Miguel Orden-Mejía +4 more
doaj +1 more source
An Evaluation of Wildlife Tourism Destinations’ Attributes, Overall Satisfaction and Revisit Intentions: A Tourist Guides’ Perspective [PDF]
African Journal of Hospitality, Tourism and Leisure, 2020 This study developed and tested a model integrating associations of tourist guides, wildlife tourism destination attributes, overall satisfaction and revisit intentions.
George Ariya +2 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source