Results 111 to 120 of about 169,635 (293)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
The Waikato Region: Major tourism issues and opportunities to facilitate tourism development: Public summary [PDF]
, 2007 A regional tourism project was commissioned by Katolyst, the Waikato Economic Development Agency, to assess the following: What is meant by regional tourism; the current views of industry stakeholders within the tourism and hospitality sectors; major ...
Walter, Naomi Jane, Zahra, Anne Louise
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source
Revista Galega de Economía, 2017 The environmental management of the hotel industry related to the governance of a mass tourist destination under the particular conditions of the protected area consideration (Biosphere Reserve) is analysed. The empirical study is performed with a sample
doaj +1 more source
Intermediaries in International Trade: direct versus indirect modes of export [PDF]
This paper contributes to the relatively new literature on the role of intermediaries in international trade. Using Italian firm-level data, we document significant differences between exporters of different types and highlight the role of country ...
Andrew B. Bernard +2 more
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FEBS Open Bio, EarlyView.Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp +13 more
wiley +1 more source
Regulating military and security services in the European Union [PDF]
, 2006 In recent years, there has been a growing disillusionment with the lack of national and international regulation of private military and security services.
Krahmann, E
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FEBS Open Bio, EarlyView.This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart +4 more
wiley +1 more source
Connection men, pushers and migrant trajectories: examining the dynamics of the migration industry in Ghana and along routes into Europe and the Gulf States [PDF]
, 2019 This paper examines the inner workings and operational logic of the array of individuals, agencies, state and non-state actors, institutions and social networks that collectively make up the migration industry in Ghana.
Awumbila, Mariama +4 more
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