Results 131 to 140 of about 169,635 (293)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Port-city mobility challenges in Ho Chi Minh City: cruise tourism infrastructure, stakeholder governance, and sustainable urban transitions

open access: yesFrontiers in Sustainable Cities
This study addresses the underexplored area of cruise tourism competitiveness in emerging Asian cities, focusing on port-city mobility and governance in Ho Chi Minh City (HCMC), Vietnam.
Trong Thanh Tran   +6 more
doaj   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

open access: yesAging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Women as social entrepreneurs in the hospitality and tourism industry: Does empowerment play a role? [PDF]

open access: yes, 2015
This paper which is a work in progress presents a qualitative study exploring the nature, motivations and extent to which female entrepreneurs use their H&T businesses as platforms for engagement in various forms of social entrepreneurship (
Kimbu, Albert N., Ngoasong, Michael
core  

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Building Capacities for Tourism Development and Poverty Reduction1 [PDF]

open access: yes, 2007
This paper advocates the application of building capacities for tourism development and poverty reduction in the locales of Elmina and Cape Coast in the Sub-Saharan country of Ghana in Africa.
Koutra, Christina
core  

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

Governança turística em destinos brasileiros: comparação entre Armação dos Búzios/RJ, Paraty/RJ e Bonito/MS

open access: yesPASOS Revista de Turismo y Patrimonio Cultural, 2016
The structure and organization of regionalized tourism brought to the political scene the term governance and with it a new way to lead innovation processes, strengthening and changing of dynamics involving tourism in a particular ...
Fábia Trentin
doaj  

Basilar Artery Occlusion Stroke Managed With Tenecteplase Versus Alteplase Before Endovascular Treatment (BAO‐TNK)

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To compare the effectiveness and safety of tenecteplase (TNK) versus alteplase (TPA) in patients with basilar artery occlusion prior to endovascular treatment (EVT). Methods In this retrospective multicenter study (BAO‐TNK), we analyzed consecutive BAO patients from 14 U.S.
Rahul R. Karamchandani   +38 more
wiley   +1 more source

The Mobility Case for Regionalism [PDF]

open access: yes, 2013
In the discourse of local government law, the idea that a mobile populace can “vote with its feet” has long served as a justification for devolution and decentralization.
Davidson, Nestor M., Foster, Sheila R.
core   +1 more source

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