Results 81 to 90 of about 169,635 (293)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Do Migrants Improve Governance at Home? Evidence from a Voting Experiment [PDF]

open access: yes
Can international migration promote better institutions at home by raising the demand for political accountability? In order to examine this question, we designed a behavioral measure of the population's desire for better governance.
Catia Batista, Pedro C. Vicente
core  

WP7 Regional/local Case Studies [PDF]

open access: yes, 2018
This report provides an in depth and transversal analysis of the policy Developing the Young Workforce (DYW) in Glasgow City Region and Aberdeen City and Aberdeenshrie Region.
Capsada-Munsech, Queralt
core  

Mapping intangibilities in creative tourism territories through tangible objects: a methodological approach for developing creative tourism offers [PDF]

open access: yes, 2019
What can people express about their places through the objects that they valorise and link to their territory? Can objects create narratives about a place's identity and collect significant cultural information that locate people in their places?
Cabeça, Sónia Moreira   +3 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

The impact of corruption distance on ownership strategies of spanish and portuguese MNEs [PDF]

open access: yes, 2017
The ownership strategy of foreign subsidiaries is an important decision for multinational enterprises (MNEs). Previous research has analyzed the effect of country dimensions on this strategy, both from the home and the host country.
Carvalho, Fernando   +2 more
core   +4 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Exploring collaborative governance and community participation in tourism and conservation—insights from Waiheke Island, New Zealand

open access: yesFrontiers in Sustainable Tourism
IntroductionBalancing conservation efforts with tourism development poses significant challenges in Small islands. Waiheke Island, located in New Zealand's inner Hauraki Gulf, is both a popular residential location and a popular tourism destination ...
Mahmoud Sarhan   +3 more
doaj   +1 more source

A profile of the world's young developing country migrants [PDF]

open access: yes
The paper uses individual level census and household survey data to present a rich profile of the young developing migrants around the world. Youth are found to comprise a large share of all migrants, particularly in migration to other developing ...
McKenzie, David J.
core  

Cyprus as a winter destination. An exploratory study [PDF]

open access: yes, 2012
Seasonal fluctuations of demand are regular in the Mediterranean islands. this could be attributed to the distinct qualities of island destinations, their vulnerability, peripherality, and isolation.
Kariopouli, S, Koutra, Christina
core   +1 more source

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