An inquiry of perceived image of urban tourism destination through tourist consumption and movement pattern [PDF]
, 2014 Identifying the factor that influence the tourist behavior and their decision making process may give a vast information for local authorities in promoting their tourism destination.
Ismail, Hairul Nizam +1 more
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A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Pengaruh Electronic Word of Mouth Terhadap Citra Destinasi Serta Dampaknya Pada Minat Dan Keputusan Berkunjung (Survei Pada Followers Aktif Akun Instagram Indtravel Yang Telah Mengunjungi Destinasi Wisata Di Indonesia) [PDF]
, 2016 The development of information and communication technology growing rapidly can be used to introduce Indonesian tourism brand. One way to introduce these brands is through electronic word of mouth on travelers using instagram.
Mawardi, M. K. (M) +2 more
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Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
PENGARUH MOTIVASI, CITRA DESTINASI, DAN SENSATION-SEEKING TERHADAP NIAT MENGUNJUNGI PULAU BELITUNG [PDF]
, 2017 MARGARETHA ESTIANA, The Effect of Motivation, Destination Image, and Sensation-seeking Towards The Intention to Visit Belitung Island. Thesis, Jakarta, Study Program of Commerce Education, Faculty of Economics, State University of Jakarta.
Estiana, Margaretha
core +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
VARIABLES OF THE IMAGE OF TOURIST DESTINATION [PDF]
The image of a destination is more than a distinguishing element; it is a component of the supply and brings more value to it. The image of a destination can be the decisive component, while the other elements re relatively alike (1).
Ban Olimpia
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Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
A social media approach to evaluating heritage destination perceptions: the case of Istanbul [PDF]
, 2016 Marketing strategies have long been considered essential for the development of successful destination brands. Their success, however, lies not upon the plans decided in closed boardrooms between tourism stakeholders, but upon the position the ...
Kladou, Stella, Mavragani, Eleni
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