Results 281 to 290 of about 97,767 (354)

Mission design of DESTINY+: Toward active asteroid (3200) Phaethon and multiple small bodies [PDF]

open access: yesActa Astronautica, 2022
DESTINY+ is an upcoming JAXA Epsilon medium-class mission to fly by the Geminids meteor shower parent body (3200) Phaethon. It will be the world's first spacecraft to escape from a near-geostationary transfer orbit into deep space using a low-thrust ...
Naoya Ozaki   +2 more
exaly   +2 more sources

Trastuzumab Deruxtecan in Previously Treated HER2-Positive Metastatic Breast Cancer: Plain Language Summary of the DESTINY-Breast01 Study

open access: yesFuture Oncology, 2021
This is a summary of the article discussing the results of the DESTINY-Breast01 study originally published in the New England Journal of Medicine. The DESTINY-Breast01 study is a clinical study in participants with a type of breast cancer called HER2 ...
Shanu Modi
exaly   +2 more sources
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Trastuzumab deruxtecan (DS-8201) in patients with HER2-expressing metastatic colorectal cancer (DESTINY-CRC01): a multicentre, open-label, phase 2 trial.

The Lancet Oncology, 2021
BACKGROUND HER2 amplification has been identified in 2-3% of patients with colorectal cancer, although there are currently no approved HER2-targeted therapies for colorectal cancer.
S. Siena   +23 more
semanticscholar   +1 more source

Abstract GS2-01: GS2-01 Trastuzumab deruxtecan vs physician’s choice in patients with HER2+ unresectable and/or metastatic breast cancer previously treated with trastuzumab emtansine: primary results of the randomized, phase 3 study DESTINY-Breast02

Cancer Research, 2023
In DESTINY-Breast01 (NCT03248492) and DESTINY-Breast03 (NCT03529110), trastuzumab deruxtecan (T-DXd) demonstrated unprecedented activity in patients (pts) with HER2+ (immunohistochemistry 3+; immunohistochemistry 2+/in situ hybridization+) advanced ...
I. Krop   +17 more
semanticscholar   +1 more source

Are Reindeer the New Buffalo? Climate Change, the Green Shift, and Manifest Destiny in Sápmi

Social Science Research Network, 2023
:In the nineteenth-century prairies, the buffalo was nearly exterminated as the result of the European economic and ecological invasion. Today in Scandinavia, reindeer are being threatened by the renewable energy transition, also known as the Green Shift.
R. Kuokkanen
semanticscholar   +1 more source

Struggling with Destiny in Karimpur, 1925-1984

, 2023
Susan Wadley first visited Karimpur - the village 'behind mud walls' made famous by William and Charlotte Wiser - as a graduate student in 1967. She returned often, adding her observations and experiences to the Wisers' field notes from the 1920s and ...
S. Wadley
semanticscholar   +1 more source

An age-specific pooled analysis of trastuzumab deruxtecan (T-DXd) in patients (pts) with HER2-positive (HER2+) metastatic breast cancer (mBC) from DESTINY-Breast01, -02, and -03.

Journal of Clinical Oncology, 2023
1006 Background: T-DXd is approved for use in pts with HER2+ unresectable or mBC after a prior anti-HER2-based regimen in the metastatic or (neo)adjuvant setting, based on the randomized phase 3 DESTINY-Breast03 study (Cortes et al.
I. Krop   +15 more
semanticscholar   +1 more source

Manifest Destiny

America’s Road to Empire, 2022
The whites are the winning race, not only in North America. It is the tradition in the USA to call this phenomenon 'Manifest Destiny'. Christians used to believe that Jesus helped the Europeans to conquer the New World.
J. Tyler
semanticscholar   +1 more source

Trastuzumab deruxtecan (T-DXd) in patients with HER2+ metastatic breast cancer with brain metastases: A subgroup analysis of the DESTINY-Breast01 trial.

Journal of Clinical Oncology, 2021
526 Background: Patients (pts) with HER2+ metastatic breast cancer (mBC) are at high risk of developing brain metastases (BMs), and treatment options are limited once BMs occur.
G. Jerusalem   +18 more
semanticscholar   +1 more source

Navigating Women’s Low Desire: Sexual Growth and Destiny Beliefs and Couples’ Well-Being

Journal of Sex Research, 2021
People’s beliefs about how to maintain sexual satisfaction have been associated with how they navigate sexual differences, but research has yet to explore the consequences of these beliefs for couples facing a distressing sexual issue.
Stephanie Raposo   +4 more
semanticscholar   +1 more source

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