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Lineage, fate, and fate potential of NG2-glia [PDF]
Brain Research, 2016 NG2 cells represent a fourth major glial cell population in the mammalian central nervous system (CNS). They arise from discrete germinal zones in mid-gestation embryos and expand to occupy the entire CNS parenchyma. Genetic fate mapping studies have shown that oligodendrocytes and a subpopulation of ventral protoplasmic astrocytes arise from NG2 cells.
Akiko Nishiyama +2 more
exaly +3 more sources
Nature Communications, 2022 The use of chimeric antigen receptor modified immune cell therapeutics has improved the treatment of a range of tumours. Here the authors explore a dual-target iPSC-derived NK cell product as a potential therapeutic for the treatment of multiple myeloma.
Frank Cichocki +22 more
doaj +1 more source
Journal of Experimental Medicine, 1921 Although the count of circulating lymphocytes in the blood stream remains constant, more lymphocytes enter the blood from the thoracic duct during 24 hours than are present in the blood at any one time. This excess of lymphocytes is not destroyed in the blood stream. The cells migrate from the blood vessels into the mucous membranes and through them to
C H, Bunting, J, Huston
openaire +2 more sources
iScience, 2023 Summary: The major lysine methyltransferase (KMT) Setdb1 is essential for self-renewal and viability of mouse embryonic stem cells (mESCs). Setdb1 was primarily known to methylate the lysine 9 of histone 3 (H3K9) in the nucleus, where it regulates ...
Roberta Rapone +7 more
doaj +1 more source
Dynamic methylation of histone H3K18 in differentiating Theileria parasites
Nature Communications, 2021 Post-translational modifications (PTM) of histones are important for epigenetic regulation in mammals. Here, Cheeseman et al. report dynamic changes in H3K18 PTM during the differentiation stages of Theileria parasites and they identify a SET-domain ...
Kevin Cheeseman +9 more
doaj +1 more source
Fitness Determinants of Influenza A Viruses
Viruses, 2023 Influenza A (IAV) is a major human respiratory pathogen that causes illness, hospitalizations, and mortality annually worldwide. IAV is also a zoonotic pathogen with a multitude of hosts, allowing for interspecies transmission, reassortment events, and ...
Emily Fate Griffin +1 more
doaj +1 more source
Frontiers in Endocrinology, 2022 Pancreatic beta cell response to glucose is critical for the maintenance of normoglycemia. A strong transcriptional response was classically described in rodent models but, interestingly, not in human cells.
Manuel Bulfoni +8 more
doaj +1 more source
Costumes and cinema: a didactic experience in the academic education of fashion designers
Projetica, 2018 This paper discusses the costumes in movies and their applicability in the academic education of fashion designers. The objectives are to understand the costumes as elements of the movie narrative and to discuss a proposal for the analysis of movie ...
Janote Pires Marques +1 more
doaj +1 more source
Nature Communications, 2021 How gene expression reactivation is promoted following DNA damage is not yet clear. Here, the authors identify a role for the human histone chaperone complex HIRA in transcription restart following UV damage independently of its function in new H3.3 ...
Déborah Bouvier +5 more
doaj +1 more source
Olig2/Plp-positive progenitor cells give rise to Bergmann glia in the cerebellum. [PDF]
, 2013 NG2 (nerve/glial antigen2)-expressing cells represent the largest population of postnatal progenitors in the central nervous system and have been classified as oligodendroglial progenitor cells, but the fate and function of these cells remain ...
Chung, S-H +4 more
core +2 more sources