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Fitness Determinants of Influenza A Viruses
Viruses, 2023 Influenza A (IAV) is a major human respiratory pathogen that causes illness, hospitalizations, and mortality annually worldwide. IAV is also a zoonotic pathogen with a multitude of hosts, allowing for interspecies transmission, reassortment events, and ...
Emily Fate Griffin +1 more
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Nature Communications, 2019 XACT is a primate-specific TE-derived lncRNA that coats active X chromosomes in pluripotent cells and may contribute to species-specific regulation of X chromosome inactivation.
Miguel Casanova +7 more
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Cells, 2018 The concept of leukocyte-tumor cell fusion as a significant driver of cancer progression has been around a long time, and has garnered growing support over the last several years. The underlying idea seems quite simple and attractive: Fusion of tumor cells (with their inherent genetic instability) with leukocytes, particularly macrophages, could ...
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Nature Communications, 2021 The heterochromatin compartment is key for genome stability and cell fate transitions. Here, by tracking the heterochromatin response to UV damage in real time, the authors reveal how heterochromatin features are preserved following a genotoxic stress ...
Anna Fortuny +6 more
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The fate of pentagastrin [PDF]
Gut, 1971 Pentagastrin is rapidly removed from the circulation of the dog. It is excreted by the liver into the bile, largely in an inactivated form. Preliminary results indicate that it meets the same fate in man.
B H, Stagg, J M, Temperley, J H, Wyllie
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LABOR EMPLOYMENT OPPORTUNITIES IN COFFEE PRODUCTION IN SOUTHERN LAO PEOPLE’S DEMOCRATIC REPUBLIC
Journal of Asian Rural Studies, 2018 General debate on the issue of labor employment is related to employment opportunity, pattern of labor employment, the contribution to labor employment, and the impact of labor employment on livelihoods. This paper examines labor employment opportunities
Dexanourath Seneduangdeth +4 more
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Future Science OAAim: We explored the generation of human induced pluripotent stem cells (iPSCs) solely through the transcriptional activation of endogenous genes by CRISPR activation (CRISPRa). Methods: Minimal number of human-specific guide RNAs targeting a limited set
Ramzey Abujarour +10 more
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Deciphering tissue structure and function using spatial transcriptomics
Communications Biology, 2022 Walker et al. review methods used to analyse spatial transcriptomics data and discuss open questions and areas of future development.
Benjamin L. Walker +4 more
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Cell Reports MedicineSummary: Although chimeric antigen receptor (CAR) T cells have demonstrated therapeutic activity in hematopoietic malignancies, tumor heterogeneity has impeded the efficacy of CAR T cells and their extension into successful solid tumor treatment.
Bi-Huei Yang +16 more
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