Results 11 to 20 of about 389,852 (268)
Lineage, fate, and fate potential of NG2-glia [PDF]
Brain Research, 2016 NG2 cells represent a fourth major glial cell population in the mammalian central nervous system (CNS). They arise from discrete germinal zones in mid-gestation embryos and expand to occupy the entire CNS parenchyma. Genetic fate mapping studies have shown that oligodendrocytes and a subpopulation of ventral protoplasmic astrocytes arise from NG2 cells.
Akiko Nishiyama +2 more
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Nature Communications, 2022 The use of chimeric antigen receptor modified immune cell therapeutics has improved the treatment of a range of tumours. Here the authors explore a dual-target iPSC-derived NK cell product as a potential therapeutic for the treatment of multiple myeloma.
Frank Cichocki +22 more
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Journal of Experimental Medicine, 1921 Although the count of circulating lymphocytes in the blood stream remains constant, more lymphocytes enter the blood from the thoracic duct during 24 hours than are present in the blood at any one time. This excess of lymphocytes is not destroyed in the blood stream. The cells migrate from the blood vessels into the mucous membranes and through them to
C H, Bunting, J, Huston
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iScience, 2023 Summary: The major lysine methyltransferase (KMT) Setdb1 is essential for self-renewal and viability of mouse embryonic stem cells (mESCs). Setdb1 was primarily known to methylate the lysine 9 of histone 3 (H3K9) in the nucleus, where it regulates ...
Roberta Rapone +7 more
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Dynamic methylation of histone H3K18 in differentiating Theileria parasites
Nature Communications, 2021 Post-translational modifications (PTM) of histones are important for epigenetic regulation in mammals. Here, Cheeseman et al. report dynamic changes in H3K18 PTM during the differentiation stages of Theileria parasites and they identify a SET-domain ...
Kevin Cheeseman +9 more
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Fitness Determinants of Influenza A Viruses
Viruses, 2023 Influenza A (IAV) is a major human respiratory pathogen that causes illness, hospitalizations, and mortality annually worldwide. IAV is also a zoonotic pathogen with a multitude of hosts, allowing for interspecies transmission, reassortment events, and ...
Emily Fate Griffin +1 more
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Frontiers in Endocrinology, 2022 Pancreatic beta cell response to glucose is critical for the maintenance of normoglycemia. A strong transcriptional response was classically described in rodent models but, interestingly, not in human cells.
Manuel Bulfoni +8 more
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Costumes and cinema: a didactic experience in the academic education of fashion designers
Projetica, 2018 This paper discusses the costumes in movies and their applicability in the academic education of fashion designers. The objectives are to understand the costumes as elements of the movie narrative and to discuss a proposal for the analysis of movie ...
Janote Pires Marques +1 more
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Identification of a dinucleotide signature that discriminates coding from non-coding long RNAs
Frontiers in Genetics, 2014 To date, the main criterion by which long ncRNAs (lncRNAs) are discriminated from mRNAs is based on the capacity of the transcripts to encode a protein. However, it becomes important to identify non-ORF-based sequence characteristics that can be used to ...
Damien eUlveling +3 more
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Cells, 2018 The concept of leukocyte-tumor cell fusion as a significant driver of cancer progression has been around a long time, and has garnered growing support over the last several years. The underlying idea seems quite simple and attractive: Fusion of tumor cells (with their inherent genetic instability) with leukocytes, particularly macrophages, could ...
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