Results 41 to 50 of about 1,264,513 (255)
Stem Cell Reports, 2014 Cell banking, disease modeling, and cell therapy applications have placed increasing demands on hiPSC technology. Specifically, the high-throughput derivation of footprint-free hiPSCs and their expansion in systems that allow scaled production remains ...
Bahram Valamehr +10 more
doaj +1 more source
Binary specification of nerve cord and notochord cell fates in ascidian embryos [PDF]
, 2001 In the ascidian embryo, the nerve cord and notochord of the tail of tadpole larvae originate from the precursor blastomeres for both tissues in the 32-cell-stage embryo. Each fate is separated into two daughter blastomeres at the next cleavage.
Makabe, Kazuhiro W. +3 more
core
, 2000 We numerically study classical time evolutions of Kaluza-Klein bubble space-time which has negative energy after a decay of vacuum. As the zero energy Witten's bubble space-time, where the bubble expands infinitely, the subsequent evolutions of Brill and
D. Bernstein +14 more
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Fate of the classical false vacuum [PDF]
, 2000 Thermalisation of configurations with initial white noise power spectrum is studied in numerical simulations of a classical one-component $\Phi^4$ theory in 2+1 dimensions, coupled to a small amplitude homogenous external field.
Borsanyi, Sz. +3 more
core +2 more sources
The fate of Ernst Ising and the fate of his model [PDF]
Journal of Physical Studies, 2017 On this, the occasion of the 20th anniversary of the "Ising Lectures" in Lviv (Ukraine), we give some personal reflections about the famous model that was suggested by Wilhelm Lenz for ferromagnetism in 1920 and solved in one dimension by his PhD student, Ernst Ising, in 1924. That work of Lenz and Ising marked the start of a scientific direction that,
Ising, Thomas +4 more
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Nerve regeneration by interferon intervention in aging brain
EMBO Molecular Medicine, 2023 Neural stem cells (NSCs) are shielded from viral infection by interferon (IFN) defense. As individuals age, activation of NSC decreases with a significant decline of stemness marker Sex‐determining region Y box 2 (Sox2) while IFN signaling enhances ...
Fanwen Wang, Duanqing Pei
doaj +1 more source