Results 51 to 60 of about 1,264,513 (255)

RSC and GRFs confer promoter directionality by restricting divergent noncoding transcription

Life Science Alliance, 2022
We show that the chromatin remodelling complex RSC and general regulatory factors (GRFs) limit transcription in the noncoding divergent direction, thereby increasing the directionality of promoters.
Andrew CK Wu, Claudia Vivori, Harshil Patel, Theodora Sideri, Fabien Moretto, Folkert J van Werven   +5 more
doaj   +1 more source

Quasi-Rip: A New Type of Rip Model without Cosmic Doomsday

, 2012
The fate of our universe is an unceasing topic of cosmology and the human being. The discovery of the current accelerated expansion of the universe significantly changed our view of the fate of the universe.
A. De Felice, Hao Wei, Long-Fei Wang, Xiao-Jiao Guo   +3 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The Ultimate Fate of Supercooled Liquids

, 2010
In recent years it has become widely accepted that a dynamical length scale {\xi}_{\alpha} plays an important role in supercooled liquids near the glass transition.
Anderson S. R., Berthier L., Biroli G., Brazovskii S. A., Bryngelson J. D., Capaccioli S., Chang S. S., Chaudhari P., Duwez P., Ediger M. D., Fischer E. W., Greet R. J., Hikima T., Hikima T., Jacob D. Stevenson, Kirkpatrick R. J., Lubchenko V., Lubchenko V., Mackowiak S. A., Mishima O., Mishima O., Naganathan A. N., Peter G. Wolynes, Pusey P. N., Rogers A. F., Russell E. V., Schmalian J., Shen T. Y., Shmyt’ko I. M., Smith R. K., Stevenson J. D., Stevenson J. D., Stevenson J. D., Stirling M. W., Sun Y., Tarjus G., Tracht U., Wilding M. C., Wolynes P. G., Wypych A., Xia X., Zaccarelli E., Zondervan R.   +42 more
core   +1 more source

Atmospheric emissions from the deepwater Horizon spill constrain air-water partitioning, hydrocarbon fate, and leak rate [PDF]

, 2011
The fate of deepwater releases of gas and oil mixtures is initially determined by solubility and volatility of individual hydrocarbon species; these attributes determine partitioning between air and water.
Aikin, KC, Angevine, WM, Atlas, EL, Blake, DR, Brock, CA, De Gouw, JA, Fahey, DW, Fehsenfeld, FC, Gao, RS, Holloway, JS, Lack, DA, Lueb, RA, Meinardi, S, Middlebrook, AM, Murphy, DM, Neuman, JA, Nowak, JB, Parrish, DD, Peischl, J, Perring, AE, Pollack, IB, Ravishankara, AR, Roberts, JM, Ryerson, TB, Schwarz, JP, Spackman, JR, Stark, H, Warneke, C, Watts, LA   +28 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Pig blastocyst-like structure models from embryonic stem cells

Cell Discovery
Pluripotent stem cells have the potential to generate embryo models that can recapitulate developmental processes in vitro. Large animals such as pigs may also benefit from stem-cell-based embryo models for improving breeding.
Jinzhu Xiang, Hanning Wang, Bingbo Shi, Jiajun Li, Dong Liu, Kaipeng Wang, Zhuangfei Wang, Qiankun Min, Chengchen Zhao, Duanqing Pei   +9 more
doaj   +1 more source

Transient-mediated fate determination in a transcriptional circuit of HIV [PDF]

, 2007
Steady-state behavior and bistability have been proposed as mechanisms for decision-making in gene circuits. However, transient gene expression has also been proposed to control cell fate with the decision arbitrated by the lifetime of the expression ...
Leor Weinberger, Michael Simpson, Roy D. Dar   +2 more
core   +1 more source

The fate of the missing spores [PDF]

, 2012
It is well-known that many species with small diaspores can disperse far during extended temporal scales (many years). However, studies on short temporal scales usually only cover short distances (in, e.g., bryophytes up to 15 m).
Bengt Gunnar Jonsson, Bente Jessen Graae, Kristoffer Hylander, Niklas Lönnell, Sebastian Sundberg   +4 more
core   +3 more sources