Results 41 to 50 of about 377,031 (287)

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

THE CONCEPT OF FATE IN AMERICAN SCIENCE FICTION LITERATURE

open access: yesNovìtnâ Osvìta, 2016
The present article is dedicated to the problem of the concept of fate functioning in the American picture of the world. The aim of the article is to investigate the concept sphere of fate in American science-fiction literature.
Yana Gryshchenko
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Otherworldly Relations in CAM Practice

open access: yesTemenos, 2021
The globalizing culture of health and wellbeing flourishes both as demand and supply, posing multiple intriguing and critical questions both to the individuals who face distress and suffering and to the surrounding society.
Terhi Utriainen
doaj   +1 more source

My Service Learning Experience [PDF]

open access: yes, 2014
This presentation produced by Destiny Brazeal, student at Virginia Commonwealth University, reflects on her experience in a service-learning ...
Brazeal, Destiny
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Qada’ Dan Qadar Perspektif Al-Qur’an Hadits dan Implikasinya Terhadap Pendidikan Agama Islam

open access: yesJ-PAI: Jurnal Pendidikan Agama Islam, 2020
Something that happens to humans is that God's will is very true, but every human being also has his own will. So that in education students can change learning outcomes by continuing to learn and make a change of changes that will run in harmony and ...
J. Nabiel Aha Putra   +1 more
doaj   +1 more source

The Honors Experience [brochure and video] [PDF]

open access: yes, 2013
Gifted and talented students become accustomed to exhibiting academic excellence throughout their K-12 careers; so much so that they learn to crave the intellectual stimulation and intrigue that is characteristic of their curricular experiences.
Savage, Destiny
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

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