Mechanism of action of the intestinal microbiota on CNS autoimmune diseases. Environmental factors shape gut microbiota composition; dysbiosis alters microbial metabolites and antigenic signals. These modulate innate and adaptive immunity, affect barrier integrity, and influence CNS‐resident cells such as microglia and astrocytes, contributing to ...
Matteo Ceccon, Francesca Ronchi
wiley +1 more source
Enteric diseases in pigs from weaning to slaughter [PDF]
The general aim of this thesis was to study enteric diseases in growing pigs, with special reference to diseases caused by Brachyspira hyodysenteriae and Lawsonia intracellularis. The occurrence of enteric diseases in “growers” is a problem of increasing
Jacobson, Magdalena
core
The gut microbiome, mucosal immunity and disease pathogenesis in humans with HIV or idiopathic CD4 lymphocytopenia and in non-human primates with SIV [PDF]
Chronic activation of the immune system is a hallmark of progressive HIV infection in humans as well as SIV infection in Asian macaque non-human primates.
Sortino, O.
core +2 more sources
Nexus of Whey Proteins, Gut Dysbiosis, and Colonic Health
Whey proteins possess antimicrobial and prebiotic properties that modulate gut microbiota by promoting beneficial bacteria like Bifidobacterium while suppressing pathogens. This modulation enhances short‐chain fatty acid production and strengthens intestinal barrier integrity, potentially alleviating dysbiosis‐related conditions such as colitis and ...
Tolulope Joshua Ashaolu +4 more
wiley +1 more source
Pectins that Structurally Differ in the Distribution of Methyl-Esters Attenuate Citrobacter rodentium-Induced Colitis [PDF]
Introduction: Pectins have anti-inflammatory properties on intestinal immunity through direct interactions on Toll-like receptors (TLRs) in the small intestine or via stimulating microbiota-dependent effects in the large intestine.
Akkerman, Renate +8 more
core +1 more source
Refining responsive antimicrobial nanomaterials from random peptide libraries via machine learning
Machine learning refines random peptide mixtures into responsive antimicrobial cocktails, yielding enhanced antibacterial efficacy and improved in vivo therapeutic effects. Abstract Antimicrobial resistance has evolved into one of the most serious threats to global public health, yet generalizable routes for refining random peptide mixtures (RPMs) into
Lin Wang +7 more
wiley +1 more source
Metatranscriptomic reads from black band disease (BBD) lesions derived from samples collected during the day and night were mapped to near‐complete BBD‐derived metagenome‐assembled genomes to profile diurnal metabolic shifts among key microbial groups. Photosynthesis genes from the cyanobacterium Roseofilum reptotaenium were highly expressed during the
Julia Y. Hung +4 more
wiley +1 more source
Searching for the gut microbial contributing factors to social behavior in rodent models of autism spectrum disorder [PDF]
Social impairment is one of the major symptoms in multiple psychiatric disorders, including autism spectrum disorder (ASD). Accumulated studies indicate a crucial role for the gut microbiota in social development, but these mechanisms remain unclear ...
Needham, Brittany D. +2 more
core
A Systems Approach to Dissecting the Role of the Mucosal Microbiome in Disease [PDF]
The microbial community harbored by the mammalian gastrointestinal tract, collectively called the gut microbiota, plays a critical role in host health, metabolism, and immunity.
Blalock, Lexie Christine
core +1 more source
Reef Sediments Can Act As a Stony Coral Tissue Loss Disease Vector [PDF]
Stony coral tissue loss disease (SCTLD) was first observed in 2014 near Virginia Key in Miami-Dade County, Florida. Field sampling, lab experiments, and modeling approaches have suggested that reef sediments may play a role in SCTLD transmission, though ...
Enochs, Ian C. +5 more
core +2 more sources

