Results 21 to 30 of about 3,773 (135)

APOE genotype influences the gut microbiome structure and function in humans and mice: relevance for Alzheimer’s disease pathophysiology [PDF]

, 2019
Apolipoprotein E (APOE) genotype is the strongest prevalent genetic risk factor for Alzheimer’s disease (AD). Numerous studies have provided insights into the pathologic mechanisms.
Corsini, Simone, Hegarty, Claire, Kellingray, Lee, Le Gall, Gwénaëlle, Minihane, Anne-Marie, Müller, Michael, Narbad, Arjan, O'Toole, Paul W., Tejera, Noemi, Tran, Tam T. T., Vauzour, David   +10 more
core   +1 more source

Bacterial Communities Are Less Diverse in a Strepsipteran Endoparasitoid than in Its Fruit Fly Hosts and Dominated by Wolbachia [PDF]

, 2023
Microbiomes play vital roles in insect fitness and health and can be influenced by interactions between insects and their parasites. Many studies investigate the microbiome of free-living insects, whereas microbiomes of endoparasitoids and their ...
Close, Shannon, Morrow, Jennifer L., Riegler, Markus, Royer, Jane E., Towett-Kirui, Sharon   +4 more
core   +2 more sources

An oligotrophic deep-subsurface community dependent on syntrophy is dominated by sulfur-driven autotrophic denitrifiers [PDF]

, 2016
Subsurface lithoautotrophic microbial ecosystems (SLiMEs) under oligotrophic conditions are typically supported by H₂. Methanogens and sulfate reducers, and the respective energy processes, are thought to be the dominant players and have been the ...
Guo, Ling, Harris, Rachel L., Kieft, Thomas L., Kuloyo, Olukayode, Kyin, Saw, Lau, Maggie C. Y., Li, Long, Linage-Alvarez, Borja, Lindsay, Melody R., Magnabosco, Cara, Oh, Youmi, Ono, Shuhei, Onstott, Tullis C., Perlman, David H., Purtschert, Roland, Sherwood Lollar, Barbara, Shwe, Henry H., Slater, Greg F., van Heerden, Esta, Wang, Wei, Wei, Siwen, Wiggins, Jessica B., Yi, Min Joo   +22 more
core   +1 more source

STUDY OF THE INTESTINAL MICROBIOTA IN RELAPSING REMITTING MULTIPLE SCLEROSIS TOWARDS NEW POTENTIAL TREATMENTS [PDF]

, 2023
Multiple sclerosis (MS) is a chronic demyelinating inflammatory disease of the central nervous system (CNS). The most frequent form is represented by the relapsing-remitting one (RRMS). Studies revealed that many genes associated with the differentiation,
GALLUZZO, Paola
core  

Hydroxytyrosol Mitigates Anxiety‐Like Behaviors After a Traumatic Experience in Aged Mice in Parallel With Increased Neurogenesis in the Ventral and Dorsal Dentate Gyrus, and Preservation of Gut Microbiota Composition

Journal of Neurochemistry, Volume 170, Issue 5, May 2026.
Hydroxytyrosol (HTyr), a phenolic compound of olive oil, exerts beneficial effects on several age‐related diseases. We previously demonstrated that oral HTyr administration in aging mice enhances hippocampal neurogenesis, known to play a role in memory formation and emotional behaviors. In the present study, we found that HTyr preferentially stimulates
Giorgio D'Andrea, Laura Bertini, Marco Costanzi, Fabiana Canini, Roberta Bernini, Andrea Fochetti, Mariangela Clemente, Silvia Proietti, Manuela Ceccarelli, Carla Caruso, Maurizia Caruso, Ferdinando Scavizzi, Marcello Raspa, Felice Tirone, Laura Micheli   +14 more
wiley   +1 more source

Emerging Paradigms in Inflammatory Disease Management: Exploring Bioactive Compounds and the Gut Microbiota [PDF]

, 2023
The human gut microbiota is a complex ecosystem of mutualistic microorganisms that play a critical role in maintaining human health through their individual interactions and with the host.
Abeir Hasan, Chiara Porro, Francesca Martina Filannino, Maria Antonietta Panaro, Mohammed-Elfatih Twfieg, Nassima Benameur, Tarek Benameur   +6 more
core   +1 more source

Atractylodes Macrocephala Polysaccharides Ameliorate Diabetic Hepatorenal Injury and Remodel Gut Microbiota in Mice

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Atractylodes macrocephala polysaccharides alleviate diabetic liver and kidney injury in HFD/STZ‐induced mice by improving gut microbiota composition, restoring intestinal barrier function, and partially correcting disturbed unsaturated fatty acid metabolism.
Jiali Wu, Xuenan Liu, Yangpeng Li, Jing Liu, Biao Jia, Hongye Peng, Qin Yuan, Wen Liu, Shengpeng Wang, Duosheng Luo, Xianglu Rong, Wenliang Lv, Jiao Guo   +12 more
wiley   +1 more source

What is the Healthy Gut Microbiota Composition? A Changing Ecosystem across Age, Environment, Diet, and Diseases. [PDF]

, 2019
Each individual is provided with a unique gut microbiota profile that plays many specific functions in host nutrient metabolism, maintenance of structural integrity of the gut mucosal barrier, immunomodulation, and protection against pathogens.
Cintoni, M, Franceschi, F (ORCID:0000-0001-6266-445X), Gasbarrini, A (ORCID:0000-0002-7278-4823), Mele, Mc (ORCID:0000-0003-0153-5819), Miggiano, Gad (ORCID:0000-0002-8627-5528), Raoul, P, Rinninella, E (ORCID:0000-0002-9165-2367)   +6 more
core   +1 more source

Attributes of intestinal microbiota composition and their correlation with clinical primary non-response to anti-TNF-α agents in inflammatory bowel disease patients [PDF]

, 2022
The largest microbial aggregation in the human body exists in the gastrointestinal tract. The microbiota in the host gastrointestinal tract comprises a diverse ecosystem, and the intestinal microbiota plays a key role in maintaining gut homeostasis. This
Al-Amrah H., Al-Hindi R., Alatawi H., Alatawy M., Alshehri D., Annese V., Bahieldin A., Edris S., Mosli M., Saadah O. I.   +9 more
core   +1 more source

Insect‐Derived Bioactives for Glycemic Control and Gut Health: A Review

Food Frontiers, Volume 7, Issue 2, March 2026.
Insect‐derived bioactive compounds (e.g., peptides, polysaccharides) effectively regulate blood glucose through dual mechanisms: directly inhibiting carbohydrate‐digesting enzymes and glucose transporters, and indirectly modulating gut microbiota to enhance intestinal barrier integrity.
Chaoyi Lv, Yuanyuan Huang, Mokhtar Dabbour, Benjamin Kumah Mintah, Ronghai He, Haile Ma   +5 more
wiley   +1 more source