Results 1 to 10 of about 809,886 (128)

Major Depressive Disorder Signatures: A Review of Artificial Intelligence (AI)-Powered Insights Into Gut Dysbiosis. [PDF]

Health Sci Rep
ABSTRACT Background and Aims Major Depressive Disorder (MDD) is a highly common neuropsychiatric disorder globally. A variety of factors contribute to the neuropathology of MDD. Microbiome research in neuropsychiatric disorders such as MDD has recently attracted attention. Indeed, the gut‐brain axis could influence the course of MDD through metabolites
Keshvari NZ, Sarkhab SAMN, Shahmoradi T, Pourashory M, Esmaeili A, Saleki K, Rezaei N.   +6 more
europepmc   +2 more sources

Milk Kefir Beverage Improves Histomorphometry, Reduces Inflammatory Infiltrates and Desulfovibrio and Increases Lactobacillus in IL-10^-/- Mice. [PDF]

J Food Sci
ABSTRACT This study aimed to evaluate the effects of milk kefir on parameters related to inflammatory bowel disease (IBD) in interleukin‐10 knockout (IL‐10−/−) mice. Sixteen C57BL/6J IL‐10−/− male mice were divided into two experimental groups. The control group (n = 8) received 0.4 mL of whole milk (UHT) and the kefir group (n = 8) received 0.4 mL of ...
Campos IX, Paris VF, Pereira MFA, Alpino GCÁ, Bernardes AL, Ávila LGM, Mishima MDV, Dias MMDS, Jangola STG, Mendes TAO, Peluzio MDCG.   +10 more
europepmc   +2 more sources

Hydroxytyrosol Mitigates Anxiety-Like Behaviors After a Traumatic Experience in Aged Mice in Parallel With Increased Neurogenesis in the Ventral and Dorsal Dentate Gyrus, and Preservation of Gut Microbiota Composition. [PDF]

J Neurochem
Hydroxytyrosol (HTyr), a phenolic compound of olive oil, exerts beneficial effects on several age‐related diseases. We previously demonstrated that oral HTyr administration in aging mice enhances hippocampal neurogenesis, known to play a role in memory formation and emotional behaviors. In the present study, we found that HTyr preferentially stimulates
D'Andrea G, Bertini L, Costanzi M, Canini F, Bernini R, Fochetti A, Clemente M, Proietti S, Ceccarelli M, Caruso C, Caruso M, Scavizzi F, Raspa M, Tirone F, Micheli L.   +14 more
europepmc   +2 more sources

Hydrogen Sulfide Produced by Gut Bacteria May Induce Parkinson’s Disease

Cells, 2022
Several bacterial species can generate hydrogen sulfide (H2S). Study evidence favors the view that the microbiome of the colon harbors increased amounts of H2S producing bacteria in Parkinson’s disease.
Kari Erik Murros
doaj   +1 more source

The Role of Gut Microbiome in the Pathogenesis of Multiple Sclerosis and Related Disorders

Cells, 2023
Multiple sclerosis (MS) is a chronic, progressive neuroinflammatory disease with a complex pathophysiological background. A variety of diverse factors have been attributed to the propagation of inflammation and neurodegeneration in MS, mainly genetic ...
Anna Dunalska, Kamila Saramak, Natalia Szejko   +2 more
doaj   +1 more source

Alteration of the gut microbiota following SARS-CoV-2 infection correlates with disease severity in hamsters

Gut Microbes, 2022
Mounting evidence suggests that the gut-to-lung axis is critical during respiratory viral infections. We herein hypothesized that disruption of gut homeostasis during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may associate ...
Valentin Sencio, Arnaud Machelart, Cyril Robil, Nicolas Benech, Eik Hoffmann, Chloé Galbert, Lucie Deryuter, Séverine Heumel, Aline Hantute-Ghesquier, Anne Flourens, Priscille Brodin, Fabrice Infanti, Virgile Richard, Jean Dubuisson, Corinne Grangette, Thierry Sulpice, Isabelle Wolowczuk, Florence Pinet, Vincent Prévot, Sandrine Belouzard, François Briand, Martine Duterque-Coquillaud, Harry Sokol, François Trottein   +23 more
doaj   +1 more source

Human fecal transplantation from stunted children promotes metabolic dysfunction in mice fed with a high-fat and high-fructose corn syrup diet

Gut Microbes
Stunting, or impaired child growth due to poor nutrition and infections, is characterized by a low height-for-age and affects 48%–56% of school-aged children worldwide. It is associated with later weight gain and chronic diseases.
Fernanda Valdez-Palomares, Lilia G. Noriega, Dana Reyes-Romo, Samuel Canizales-Quinteros, Rafael Nambo-Venegas, Citlaltepetl Salinas-Lara, Armando Tovar-Palacio, Marta Menjivar, Barbara Peña-Espinoza, Guadalupe Ortiz, Berenice Palacios-González   +10 more
doaj   +1 more source

Cross‐Sectional Associations Between Gut Microbiota and Neuroimaging Changes in Post‐COVID‐19 Condition

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
In patients with post‐COVID‐19 condition, a significant shift in gut microbiota composition can be observed, marked by a decrease in butyrate‐producing taxa. Relevant taxa correlate with clinical symptoms, structural and functional brain changes, which suggests potential therapeutic targets and highlight the need for further investigation in their ...
Sophie Wetz, Ravi Dadsena, Nicole Treichel, Ana S. Costa, Anna Hofmann, Sandro Romanzetti, Thomas Clavel, Kathrin Reetz, Julia Walders   +8 more
wiley   +1 more source

Gallstone formation and hepatobiliary tumour risk: Clinical implications of the bile acid–gut microbiota axis

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
1. Irregular dietary patterns (e.g., late breakfast, reduced meal frequency) upregulate the bai gene cluster by disrupting cholecystokinin (CCK) release rhythms and gut microbiota circadian rhythms, leading to increased production of secondary bile acids, particularly DCA. High‐carbohydrate dietary patterns increase gallstone risk (OR = 1.329).
Rui Li, Yong Zhang, Kaishuang Cai, Shaojun Deng, Chaofeng Tan, Yunjie Li, Wenjin Liang   +6 more
wiley   +1 more source

Modulating the Gut‐Microbiota‐Brain Axis in Alzheimer's Disease: Therapeutic Potential of Nutritional and Metabolic Factors

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
This review systematically examines the role of gut microbiota modulation in Alzheimer's disease, focusing on how microbial metabolites and dietary nutrients influence cognitive function and AD pathology, as well as the neuroprotective effects through the gut‐brain axis.
Binyue Xu, Xuhuan Li, Shangling Dong, Zheyuan Zhang, Dong Jin, Guoping Li, Jiesheng Wang   +6 more
wiley   +1 more source