Results 191 to 200 of about 442,419 (258)

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Brain parcellation for TMD neuroimaging: a critical narrative review. [PDF]

BDJ Open
Savychuk N, Pekhno V, Liakhovska A, Sulik R, Riabko I.   +4 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Recommendations and considerations for hydroxyl radical protein footprinting-mass spectrometry. [PDF]

Nat Methods
Wecksler AT, Wang L, Bernstein LJ, Huang RY, Gupta S, Kristensen LG, Ralston CY, Sobott F, Sun Y, Brenowitz M, Farquhar ER, Chance MR, Kuang XC, Gross ML, Jones LM, Novak P, Misra SK, Sharp JS.   +17 more
europepmc   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Susceptibility-Based MRI in Cerebral Arteriovenous Malformations: From Venous Drainage to Physiological Biomarkers-A Narrative Review. [PDF]

Biomedicines
Wiśniewski K, Iimori T, Inoue Y.
europepmc   +1 more source

Open-Window Mapping for Accessory Pathway Ablation: Influence of Catheter Design on Mapping Performance. [PDF]

J Arrhythm
Iimura K, Yagishita A, Iijima A, Amino M, Ikari Y, Yoshioka K.   +5 more
europepmc   +1 more source

Spatiotemporal Stability of Persistent Atrial Fibrillation Sources: Stable Source or Disease Progression? [PDF]

J Cardiovasc Dev Dis
Gagyi RB, Minciuna IA, Vamos M, Nemes A, Ruppersberg P, Bories W, Szili-Torok T.   +6 more
europepmc   +1 more source