Results 61 to 70 of about 442,419 (258)
Masterplan Kawasan Lubuak Tampuruang untuk Pengembangan Desa Wisata Guo
Warta Pengabdian AndalasThis community service activity was chosen to map the Guo Village area to identify existing potentials, such as tourism, regional development, and agriculture.
Nurhamidah +7 more
doaj +1 more source
Сибирский лесной журнал, 2014 All vegetation sites as objects of burning are structural complexes of various fuels. Especially complex are forest biogeoceonoses. For practical use, pyrological characteristics of vegetation are reflected on plans and maps showing both general one ...
A. V. Volokitina, T. M. Sofronova
doaj
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Applying the ELSA Framework to Assess Ecosystem Vulnerability in Wetlands of the Aral Sea Region [PDF]
E3S Web of ConferencesWetlands are vital ecosystems that provide numerous ecological services, including water purification, flood control, and wildlife habitat. However, wetlands are under threat due to human activities and climate change.
Reymov Polat +3 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Frontiers in Neuroscience, 2017 Brain function is often characterized by the connections and interactions between highly interconnected brain regions. Pathological disruptions in these networks often result in brain dysfunction, which manifests as brain disease.
Yong Jeong +14 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Improving overlay maps of science: Combining overview and detail
Quantitative Science Studies, 2022 Abstract Overlay maps of science are global base maps over which subsets of publications can be projected. Such maps can be used to monitor, explore, and study research through its publication output. Most maps of science, including overlay maps, are flat in the sense that they visualize research fields at one single level.
openaire +3 more sources