Results 81 to 90 of about 442,419 (258)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Gigapixel Imaging and Photogrammetry: Development of a New Long Range Remote Imaging Technique

open access: yesRemote Sensing, 2012
The use of terrestrial remote imaging techniques, specifically LiDAR (Light Detection And Ranging) and digital stereo-photogrammetry, are widely proven and accepted for the mapping of geological structure and monitoring of mass movements. The use of such
George Bevan   +2 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Is there a Cretan Supradetachment Basin? Insights From Detailed Mapping on Northwestern Crete (Greece)

open access: yesTektonika
The island of Crete in the South Aegean forearc exposes a fragmented and dismembered non-metamorphic nappe stack that is separated from underlying, exhumed high-pressure, low-temperature metamorphic rocks by an extensional detachment system.
Willem Jan Zachariasse   +1 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Slope stability assessment of road cut slopes along NH 107 (Kund-Sonprayag), Gharwal Himalaya, India

open access: yesResults in Earth Sciences
Slope instability is one of the major problems for the road cut slopes in the hilly areas. Detailed geological mapping with emphasis on the structural data can be a best approach to study these road cut slopes and helps to delineate the active failure ...
Ashish Kumar Kaushik   +2 more
doaj   +1 more source

Mapping Complex Urban Land Cover from Spaceborne Imagery: The Influence of Spatial Resolution, Spectral Band Set and Classification Approach

open access: yesRemote Sensing, 2016
Detailed land cover information is valuable for mapping complex urban environments. Recent enhancements to satellite sensor technology promise fit-for-purpose data, particularly when processed using contemporary classification approaches.
Rahman Momeni   +2 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Mapping soil property classes over a large territory with multiple soilscapes by digital extrapolations of legacy detailed soil maps: A case study in Karnataka -South India

open access: yesGeoderma
Using detailed soil maps to calibrate DSM models could be an alternative to point observations, as they would account for local soil patterns more accurately than the sparse sets of soil profiles classically used in broad-scale DSM applications. However,
Philippe Lagacherie, S. Dharumarajan
doaj   +1 more source

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