Results 81 to 90 of about 442,419 (258)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Gigapixel Imaging and Photogrammetry: Development of a New Long Range Remote Imaging Technique
The use of terrestrial remote imaging techniques, specifically LiDAR (Light Detection And Ranging) and digital stereo-photogrammetry, are widely proven and accepted for the mapping of geological structure and monitoring of mass movements. The use of such
George Bevan +2 more
doaj +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
The island of Crete in the South Aegean forearc exposes a fragmented and dismembered non-metamorphic nappe stack that is separated from underlying, exhumed high-pressure, low-temperature metamorphic rocks by an extensional detachment system.
Willem Jan Zachariasse +1 more
doaj +1 more source
A detailed mapping of the food industry in the European single market: similarities and differences in market structure across countries and sectors. [PDF]
Van Dam I +4 more
europepmc +1 more source
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Slope stability assessment of road cut slopes along NH 107 (Kund-Sonprayag), Gharwal Himalaya, India
Slope instability is one of the major problems for the road cut slopes in the hilly areas. Detailed geological mapping with emphasis on the structural data can be a best approach to study these road cut slopes and helps to delineate the active failure ...
Ashish Kumar Kaushik +2 more
doaj +1 more source
Detailed land cover information is valuable for mapping complex urban environments. Recent enhancements to satellite sensor technology promise fit-for-purpose data, particularly when processed using contemporary classification approaches.
Rahman Momeni +2 more
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Using detailed soil maps to calibrate DSM models could be an alternative to point observations, as they would account for local soil patterns more accurately than the sparse sets of soil profiles classically used in broad-scale DSM applications. However,
Philippe Lagacherie, S. Dharumarajan
doaj +1 more source

