Results 61 to 70 of about 6,693,654 (294)

Safety and Effectiveness of a High‐Dose, Tailored Tissue Plasminogen Activator Therapy Protocol: A Joint Pediatric Hematology and Cardiac ICU Quality Improvement Initiative Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak, Oded Gilad, Yael Feinstein, Sigal Nakav, Ofer Schiller, Joanne Yacobovich   +5 more
wiley   +1 more source

Nanostructured lipid carriers for MicroRNA delivery in tumor gene therapy

Cancer Cell International, 2018
MicroRNAs (miRNAs), which are endogenous about 20–23 nucleotides non-coding RNAs, have been acted as post-transcriptional regulators of gene expression.
Hairong Wang, Shiming Liu, Li Jia, Fengyun Chu, Ya Zhou, Zhixu He, Mengmeng Guo, Chao Chen, Lin Xu   +8 more
doaj   +1 more source

Global Efforts to Reduce Paediatric Cancer Care Disparities in Radiotherapy: A Decade Change

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We present an update on the status, needs and challenges faced by paediatric imaging and radiotherapy (RT) programmes globally after a previous survey conducted by the International Atomic Energy Agency (IAEA) 10 years prior. Methods We developed and distributed a 121‐question survey to radiation oncologists, medical physicists and ...
Raymond B. Mailhot Vega, Daniel J. Indelicato, Jeanette Parkes, Natia Esiashvili, Josué Hernández Benítez, Miriam Mikhail‐Lette, Olivera Cirajc Bjelac, Daniel Berger, Eva Ciurana, Yavuz Anacak, Lisbeth Cordero‐Mendez   +10 more
wiley   +1 more source

Interfacial stress decoupling enables stable palladium-based hydrogen sensing

Nature Communications
Interfacial adhesion between the sensing layer and supporting substrate critically governs the long-term stability of electrical molecular sensors. However, achieving a robust heterointerface remains challenging due to the intrinsic lattice mismatch ...
Rui Gao, Guozhu Zhang, Xiaoyuan Wang, Yujing Xu, Chao Zhang, Linfeng Li, Zeyu Wang, Bowei Zhang, Kazuki Nagashima, Takeshi Yanagida, Fu-Zhen Xuan   +10 more
doaj   +1 more source

Improved depth sensitivity by separation of excitation and detection coils [PDF]

, 2019
A laparoscopic probe for magnetic sentinel node biopsy has been developed. Superparamagnetic iron oxide nanoparticles (SPIONs) are used as a tracer. They are selectively detected by Differential Magnetometry (DiffMag).
van de Loosdrecht, Melissa Mathilde, ten Haken, Bernard, Krooshoop, Hendrikus J.G.   +2 more
core   +1 more source

Quantifying the hidden costs of imperfect detection for early detection surveillance [PDF]

, 2019
The global spread of pathogens poses an increasing threat to health, ecosystems and agriculture worldwide. As early detection of new incursions is key to effective control, new diagnostic tests that can detect pathogen presence shortly after initial ...
Parnell, S. R., van den Berg, Femke, Van Den Berg, F., Mastin, Alexander J., Parnell, Stephen R., Van Den Bosch, F., Mastin, A. J., van den Bosch, Frank   +7 more
core   +1 more source

Neuropsychological and Educational Outcomes in Shwachman–Diamond Syndrome—A Report From the North American Shwachman–Diamond Syndrome Registry

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Shwachman–Diamond syndrome (SDS) is a rare autosomal recessive ribosomopathy characterized by bone marrow failure and multisystem involvement, with emerging evidence of associated neurocognitive impairment. Methods We conducted a retrospective study of 240 individuals with biallelic Shwachman–Bodian–Diamond syndrome (SBDS) mutations
Jane Koo, Melissa Gerstle, Leah Cheng, Richard Cooper, Katherine Coyne, Claire Dusa, Naomi E. Joffe, Diana Schwarz, Sarah Steltz, Akiko Shimamura, Kasiani C. Myers, Thea Quinton   +11 more
wiley   +1 more source

Sentinel node biopsy in prostate and bladder cancer using magnetic nanoparticles and a new magnetic detection technique [PDF]

, 2018
Sentinel node biopsy in prostate and bladder cancer using magnetic nanoparticles and a new magnetic detection ...
Molenaar, Lennert, Pouw, Joost Jacob, van Baarlen, J., ten Haken, Bernard, Broeders, Ivo Adriaan Maria Johannes, Roelink, H., van Baarlen , J.   +6 more
core   +1 more source

A Situational Assessment of the Diagnostic Landscape and Organizational Readiness to Implement Next‐Generation Sequencing at Two Childhood Cancer Treatment Centers in Ghana

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Next‐generation sequencing (NGS) has emerged as a promising approach to improve diagnostic accuracy, but its feasibility in low‐ and middle‐income countries remains unknown. This study characterized the diagnostic landscape and assessed organizational readiness for NGS implementation at two childhood cancer treatment centers in Accra ...
Melissa Carvalho, Emmanuella Amoako, Nihad Salifu, Lily Gloria Tagoe, Yaw Bediako, Michelle Hermiston, Catherine Segbefia   +6 more
wiley   +1 more source

Droplet digital polymerase chain reaction for rapid broad-spectrum detection of bloodstream infections [PDF]

, 2019
Contains fulltext : 218675.pdf (Publisher’s version ) (Open Access)The droplet digital polymerase chain reaction (ddPCR) is a novel molecular technique that allows rapid quantification of rare target DNA sequences. Aim of this study was
Heiman F. Wertheim, Morsche, R.H.M. te, Yannick Wouters, Chantal P. Bleeker‐Rovers, Bleeker-Rovers, Chantal P., Roelofs, Hennie M.J., te Morsche, René H., Wertheim, H.F.L., Wanten, Geert J.A., Wanten, Geert JA, Hennie M. J. Roelofs, Bleeker-Rovers, C.P., Christenhusz, A., Christenhusz, Anke, Wertheim, Heiman F, Daisy Dalloyaux, Bleeker-Rovers, Chantal P, Roelofs, Hennie MJ, Wanten, G.J.A., René H. te Morsche, Roelofs, H.M.J., Anke Christenhusz, Wertheim, Heiman F., Dalloyaux, D., Te Morsche, René H, Dalloyaux, Daisy, Geert J. A. Wanten, Wouters, Y., Wouters, Yannick   +28 more
core   +3 more sources