Results 61 to 70 of about 9,691,705 (303)

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Learning to Detect Vehicles by Clustering Appearance Patterns

open access: yes, 2015
This paper studies efficient means for dealing with intra-category diversity in object detection. Strategies for occlusion and orientation handling are explored by learning an ensemble of detection models from visual and geometrical clusters of object ...
Ohn-Bar, Eshed, Trivedi, Mohan M.
core   +1 more source

Detecting binomiality

open access: yesAdvances in Applied Mathematics, 2015
Binomial ideals are special polynomial ideals with many algorithmically and theoretically nice properties. We discuss the problem of deciding if a given polynomial ideal is binomial. While the methods are general, our main motivation and source of examples is the simplification of steady state equations of chemical reaction networks.
Carsten Conradi, Thomas Kahle
openaire   +2 more sources

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul   +13 more
wiley   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel   +3 more
wiley   +1 more source

Developing Single Nucleotide Polymorphisms for Identification of Cod Products by RAD-Seq

open access: yesAnimals, 2020
The increase in the rate of seafood fraud, particularly in the expensive fishes, forces us to verify the identity of marine products. Meanwhile, the definition of cod lacks consistency at the international level, as few standards and effective ...
Shoujia Jiang   +4 more
doaj   +1 more source

Continuous Wavelet Transform and Hidden Markov Model Based Target Detection [PDF]

open access: yes, 2014
Standard tracking filters perform target detection process by comparing the sensor output signal with a predefined threshold. However, selecting the detection threshold is of great importance and a wrongly selected threshold causes two major problems ...
Efe, M., Tuğaç, S.
core   +1 more source

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash   +4 more
wiley   +1 more source

Effects of loss on the phase sensitivity with parity detection in an SU(1,1) interferometer

open access: yes, 2018
We theoretically study the effects of loss on the phase sensitivity of an SU(1,1) interferometer with parity detection with various input states. We show that although the sensitivity of phase estimation decreases in the presence of loss, it can still ...
Jiang, Wei   +5 more
core   +1 more source

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