Results 81 to 90 of about 6,693,654 (294)

Varying Indian crustal front in the southern Tibetan Plateau as revealed by magnetotelluric data

Earth, Planets and Space, 2017
In the southern Tibetan plateau, which is considered to be the ongoing India–Eurasia continental collision zone, tracing of the Indian crustal front beneath Tibet is still controversial.
Chengliang Xie, Sheng Jin, Wenbo Wei, Gaofeng Ye, Letian Zhang, Hao Dong, Yaotian Yin   +6 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

DUSP8 phosphatase: structure, functions, expression regulation and the role in human diseases

Cell & Bioscience, 2019
Dual-specificity phosphatases (DUSPs) are a subset of protein tyrosine phosphatases (PTPs), many of which dephosphorylate the residues of phosphor-serine/threonine and phosphor-tyrosine on mitogen-activated protein kinases (MAPKs), and hence are also ...
Tao Ding, Ya Zhou, Runying Long, Chao Chen, Juanjuan Zhao, Panpan Cui, Mengmeng Guo, Guiyou Liang, Lin Xu   +8 more
doaj   +1 more source

MPOE Based Adaptive Multiuser Detection

, 2008
Introduction . Continuous Time Discrete Time . MPOE Based Methods: Introduction . Probability of Error Expressions Probability Distribution of the Decision Statistics Joint Probability Conditional Probability .
Multiuser Detection Brief
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

OVARIAN CANCER DETECTION BY LOGICAL ANALYSIS OF PROTEOMIC DATA 1

, 2008
Ovarian cancer detection by ...
Ovarian Cancer Detection Lad
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Progranulin promotes glioma progression via interaction with cathepsin D and serves as a diagnostic and prognostic biomarker

Discover Oncology
Progranulin (PGRN) plays a crucial role in the progression of various tumor types, making it a potentially valuable biomarker. However, the roles of PGRN vary across tumor types.
Chunming Zhao, Jiamei Guo, Zhong Zhou, Xulong Huang, Yifan Hai, Wenbo Gao, Chaohang Chen, Guokai Dong, Hongxing Cai, Shanshan Li   +9 more
doaj   +1 more source

Detecting binomiality

Advances in Applied Mathematics, 2015
Binomial ideals are special polynomial ideals with many algorithmically and theoretically nice properties. We discuss the problem of deciding if a given polynomial ideal is binomial. While the methods are general, our main motivation and source of examples is the simplification of steady state equations of chemical reaction networks.
Carsten Conradi, Thomas Kahle
openaire   +3 more sources