Results 101 to 110 of about 9,691,705 (303)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Development and pilot testing of INTERVENER, a web-based tool to match barriers to the cancer continuum organization to evidence-based interventions

BMC Health Services Research
Background Barriers to the cancer continuum organization and interventions to approach them have been identified; however, there is a lack of a tool matching them.
Isabel Mosquera, Hannah Theriault, Dominique Meunier, Partha Basu, Andre L. Carvalho   +4 more
doaj   +1 more source

Accurate Pulmonary Nodule Detection in Computed Tomography Images Using Deep Convolutional Neural Networks

, 2017
Early detection of pulmonary cancer is the most promising way to enhance a patient's chance for survival. Accurate pulmonary nodule detection in computed tomography (CT) images is a crucial step in diagnosing pulmonary cancer.
AAA Setio, DS Alberts, EL Torres, RL Siegel, S Armato   +4 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Object Detection in 20 Years: A Survey

, 2019
Object detection, as of one the most fundamental and challenging problems in computer vision, has received great attention in recent years. Its development in the past two decades can be regarded as an epitome of computer vision history.
Guo, Yuhong, Shi, Zhenwei, Ye, Jieping, Zou, Zhengxia   +3 more
core  

Measuring the absolute photo detection efficiency using photon number correlations

, 2006
We present two methods for determining the absolute detection efficiency of photon-counting detectors directly from their singles rates under illumination from a nonclassical light source.
Aytür, Eberhard, Gasparoni, Heidmann, Klyshko, Knill, Kwiat, Kwiat, O'Brien, Rarity, Sanaka   +10 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

A comprehensive study of sparse codes on abnormality detection

, 2016
Sparse representation has been applied successfully in abnormal event detection, in which the baseline is to learn a dictionary accompanied by sparse codes.
Moeslund, Thomas B., Olsen, Søren Ingvor, Pan, Hong, Ren, Huamin   +3 more
core  

Entanglement and quantum discord dynamics of two atoms under practical feedback control

, 2011
We study the dynamics of two identical atoms resonantly coupled to a single-mode cavity under practical feedback control, and focus on the detection inefficiency.
Bin Luo, Hong Guo, M. A. Nielson, Yang Li   +3 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source