Results 91 to 100 of about 6,693,654 (294)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Misfiring Detection in 8 Cylinders Turbo Engine
, 2001 Both European parliament and Council have defined he engine misfiring, on the 98/69/EC directive, as follows: "lack of combustion in the cylinder of a positive ignition engine due to the spark absence, poor fuel metering, poor compressione or any other ...
Siviero C +3 more
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
, 2016 The objective of this work is to recognize object categories in paintings, such as cars, cows and cathedrals. We achieve this by training classifiers from natural images of the objects. We make the following contributions: (i) we measure the extent of the domain shift problem for image-level classifiers trained on natural images vs paintings, for a ...
Crowley, Elliot J., Zisserman, Andrew
openaire +1 more source
An immunological approach to intrusion detection [PDF]
, 2000 This paper presents an examination of intrusion detection schemes. It discusses traditional views of intrusion detection, and examines the more novel, but perhaps more effective, approach to intrusion detection as modeled on the human immune system ...
Watkins, A., Andrew Watkins
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The value of ultrasound to differentiate between benign and malignant duct ectasia
مجلة كلية الطب, 2014 Background: Mammary duct ectasia is defined as dilated duct larger than 2 mm in diameter seen in fibrocystic changes, ductal epithelial hyperplasia, papiloma, DCIS. US has a significant role in diagnostic breast imaging.
Enam A. AL -Tememy +3 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Unsupervised clustering approach for network anomaly detection
, 2012 This paper describes the advantages of using the anomaly detection approach over the misuse detection technique in detecting unknown network intrusions or attacks.
Syarif, Iwan +2 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source