Results 41 to 50 of about 3,670,867 (254)

Investigation of the Behavioral Characteristics of Dogs Purpose-Bred and Prepared to Perform Vapor Wake® Detection of Person-Borne Explosives

Frontiers in Veterinary Science, 2018
Specialized detector dogs are increasingly being utilized for the detection of modern threats. The Vapor Wake® (VW) dog was developed to create a dog phenotype ideally suited for detecting hand-carried and body-worn explosives. VW dogs (VWDs) are trained
Lucia Lazarowski, Lucia Lazarowski, Pamela Sue Haney, Jeanne Brock, Terry Fischer, Bart Rogers, Craig Angle, Jeffrey S. Katz, L. Paul Waggoner   +8 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Investigation of measures to reduce dog attacks and promote responsible ownership amongst dog owners with dog control issues in the UK [PDF]

, 2021
The overall aim of the project is to identify methods to reduce dog attacks and dog control issues as well as provide evidence-based recommendations to promote responsible dog ownership amongst owners with dog control issues.
Miles, L., Nurse, A., Guest, C.
core   +1 more source

Short Circuit Fault Detection against High Thermal Background Using a Two-Level Scheme Based on DoG Filter

Complexity, 2021
Short circuit is a key factor which drastically affects the efficiency of metal electrorefining. Infrared image of the intercell busbar region is used to perform short circuit detection. To cope with the high thermal background, a two-level short circuit
Xin Li, Yonggang Li, Hongqiu Zhu, Renchao Wu, Can Zhou   +4 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

A detection dog for obstructive sleep apnea

Sleep and Breathing, 2018
We sought to assess whether a dog can be trained to distinguish obstructive sleep apnea patients from healthy controls based on the olfactory detection of urine.Urine samples were collected from 23 adult male obstructive sleep apnea patients and from 20 voluntary adult male volunteers. Three dogs were trained through reinforced operant conditioning.Two
Bachour Adel, Koskinen Anni, Vaarno Jenni, Bäck Leif, Klockars Tuomas, Bachour Adel, Koskinen Anni, Vaarno Jenni, Bäck Leif, Klockars Tuomas   +9 more
openaire   +2 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Training of Ecological Detection Dogs for Wolf Scat (Canis lupus)

Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Animal Science and Biotechnologies, 2021
Detection dogs for wolf scat can assist in conservation-monitoring of wolves. In this pilot project, the first encounters of experienced detection dogs with wolf scat were documented.
Hilde VERVAECKE, Ellen VAN KRUNKELSVEN, Koen VAN DEN BERGE   +2 more
doaj   +1 more source

Detection and molecular characterization of sapoviruses in dogs

Infection, Genetics and Evolution, 2016
Caliciviruses are important human and animal pathogens. Novel caliciviruses have been identified recently in dogs, raising questions about their pathogenic role and concerns regarding their zoonotic potential. By screening stool samples of young or juvenile dogs using RT-PCR assays, sapoviruses (SaVs) were found in 7/320 (2.2%) samples of animals with ...
Bodnar, Livia, DI MARTINO, Barbara, DI PROFIO, FEDERICA, MELEGARI, IRENE, Lanave, Gianvito, Lorusso, Eleonora, Cavalli, Alessandra, Elia, Gabriella, Bányai, Krisztián, MARSILIO, Fulvio, Buonavoglia, Canio, Martella, Vito   +11 more
openaire   +3 more sources